Journal of Life Science (생명과학회지)

Korean Society of Life Science (한국생명과학회)
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Symbionin Produced by Intracellular Symbionts, which has Molecular Chaperone Activity and Novel Histidine Protein Kinase

Symbionin은 세포내 공생미생물이 생산하는 molecular chaperone 활성을 가진 색다른 histarmine protein kinase이다.

  • 권오유 (충남대학교 의과대학 해부학교실) ;
  • 김원식 (충남대학교 의과대학 해부학교실)
  • Published : 1996.09.01
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Abstract

Symbionin, ahomologue of E. coli GroEL, produced by an intracellular symbiont of the pea aphid , has molecular chaperone activity bothin vitro and in vivo, and it is able to tarnsfer its high-energy phospholy group to other compounds through its autophosphorylation and phosphotransferase activity. The symbionin is a novel histidine protein Kinase and a senor molecular of the two-component pathway.

대장균의 GroEL과 상동성을 가지는 symbionin이 진딧물의 세포내 곤생미생물에서 유일하게 생산된다. 이것은 in vitro와 in vivo에서 moecular chaperone 활성을 가지는 것과 함께 자가인산화(autophosphory-lation)와 인산기전이효소(phosphotransferase)의 활성에 의해서 고에너지 인산기를 다른 곳에 줄 수 있다. Symbionin은 two component pathway의 센서분자의 역할을 하며, 지금까지 알려진 것과는 다른 성질을 가진 protein Kinase이다.

Keywords

References

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