Culture Conditions Affecting the Molecular Weight Distribution of Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Synthesized by Alcaligenaes sp. SH-69

  • Published : 1996.09.01

Abstract

The weight average molecular weight of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) synthesized by Alcaligenes sp. SH-69 was altered between $3.2$\times$10^5$ and $1.1$\times$10^6$ depending upon various culture conditions. It appeared that culture conditions favorable for the efficient production of copolyesters promoted the formation of higher molecular weight copolyesters. Polydispersity indices of isolated copolyesters were in the range of 1.5 to 2.5.

Keywords

References

  1. FEMS Microbiol. Rev. v.103 Studies on copolyester synthesis by Rhodococcus ruber and factors influencing the molecular mass of polyhydroxybutyrate accumulated by methylobacterium extorquens and Alcaligenes eutrophus Anderson, A.J.;D.R. Williams;B. Taidi;E.A. Dawes;D.F. Ewing
  2. FEMS Microbiol. Rev. v.103 Physical properties of poly(hydroxybutyrate) and copolymers of hydroxybutyrate and hydroxyvalerate Barham, P.J.;P. Barker;S.J. Organ
  3. Appl. Microbiol. Biotechnol. v.37 Production of poly-β-hydroxybutyrate from methanol: characterization of a new isolate of Methylobacterium extorquens Bourque, D.;B. Ouellette;G. Andre;D. Groleau
  4. Eur. J. Appl. Microbiol. Biotechnol. v.6 A rapid method for the determination of poly-β-hydroxybutyric acid in microbial biomass Braunegg, G.;B. Sonnleitner;R.M. Lafferty
  5. Biotechnol. Lett. v.16 The effect of substrate on the molecular weight of poly-β-hydroxybutyrate produced by Azotobacter vinelandii UWD Chen, G.-Q.;W.J. Page
  6. Appl. Microbiol. Biotechnol. v.37 Effect of nutrient defficiency on accumulation and relative molecular weight of poly-β-hydroxybutyric acid by methylotrophic bacterium, Pseudomonas 135 Daniel, M.;J.H. Choi;J.H. Kim;J.M. Lebeault
  7. Microbial polyesters Doi, Y.
  8. Proc. 11th Australian Biotechnol. Conf. (Perth, Australia) Continuous culture evaluation of biopolymer production by Alcaligenes sp. SH-69 Jang, J.-H.;Y.H. Rhee;P.L. Rogers
  9. Biotechnol. Lett. v.14 Accumulation of copolymes consisting of 3-hydroxybutyrate and 3-hydroxyvalerate by Alcaligenes sp. SH-69 in batch culture Kim, G.J.;K.Y. Yun;K.S. Bae;Y.H. Rhee
  10. Pharm. Ind. v.45 Poly-D(-)-3-hydroxybutyric acid (PHBA)-a biodegradable carrier for long term medication dosage. 1. Development of parenteral matrix tablets for long term application of pharmaceuticals Korsarko, W.;B. Wabnegg;G. Braunegg;R.M. Lafferty;F. Strempfl
  11. Biotechnology Microbial production of poly-β-hydroxybutyric acid Lafferty, R.M.;B. Korsatko;W. Korsatko;H.J. Rehm(ed.);G. Reed(ed.)
  12. Bio/Technology v.13 Production of polyhydroxyalkanoates, a family of biodegradable plastics and elastomers, in bacteria and plants Poirier, Y.;C. Nawrath;C. Somerville
  13. Aust. Biotechnol. v.2 Biopolymer production by an Alcaligenes sp. for biodegradable plastics Rhee, Y.H.;J.-H. Jang;P.L. Rogers
  14. Biotechnol. Lett. v.15 Production of copolyester consisting o 3-hydroxybutyrate and 3-hydroxyvalerate by fed-batch culture of Alcaligenes sp. SH-69 Rhee, Y.H.;J.-H. Jang;P.L. Rogers
  15. Biodegradable plastics and polymers Control of molecular weight distribution and mole fraction in poly(-D(-)-3-hydroxyalkanoate) (PHA) production by Alcaligenes eutrophus Shimizu, H.;S. Tamura;Y. Ishihara;S. Shioya;K. Suga;Y. Doi(ed);K. Fukuda(ed)
  16. Appl. Microbiol. Biotechnol. v.27 Control o molecular weight of poly-β-hydroxybutyric acid produced in fed-batch culture of Protomonas extoquens Suzuki, T.;H. Deguchi;T. Yamane;S. Shimizu;K. Gekko
  17. Biotechnol. Lett. v.17 Effect of pH on the molecular weight of poly-3-hydroxybutyric acid produced by Alcaligenes sp Yeom, S.H.;Y.J. Yoo
  18. J. Ferment. Bioeng. v.80 Effect of amino acid additions on molar fraction of 3-hydroxyvalerate in copolyester of 3-hydroxybutyrate and 3-hydroxyvalerate synthesized by Alcaligenes sp Yoon, J.S.;J.Y. Kim;Y.H. Rhee