Invasive Thymoma Originating from Right Pleura with Normal Thymus A case Report

흉막에서 발생한 침습성 흉선종,정상 흉선을 가진 예

  • 박희철 (한림대학교 의과대학 흉부외과학교실) ;
  • 옥창석 (한림대학교 의과대학 흉부외과학교실, 해부병리학교실, 방사선학교실)
  • Published : 1996.12.01

Abstract

Thymoma Is an anterior mediastinal tumor, arising from the thymus, but occasionally has ectopic focus such as neck, trachea, thyroid, pulmonary hilum, lung parenchyme and pleura. Forty-two year old male patient was admitted due to progressive development of shortness of breath in 4 months. He had a history of exposure to asbestos for About 10 years duration In recent 15 years. Radiologically, multiple pleural masses were seen rom apex to diaphrAgm, with no evidence of anterior mediastinal mass,with fluid in right pleural cavity. Closed thoracotomy drainage with open biopsy were performed. Effusion cell block showed many T cell marker positive Lymphocytes & some epithelial cells compatible with thymoma, and the tissue also showed cortical type thymoma. Pleuropneumonectomy and thymectomy followed by 60 Gy radiation therapy were done and the patient is well 8 months postoperatively. The pleura is markedly thickened by the invasion of thymoma and the interstitial space of the lung tissue,but the normal appearance of thymus was present in remote area (Masaoka classification IVa). We report a case of ectopic invasive thymoma arising from the right pleura with intact thymus.

42세 남자는 약 10년간 석면에 노출되는 직업에 종사하다가 그만둔지 5년 후, 진행하는 호흡곤란을 주소로 검사를 받던중 우측 늑막에 다양한 크기의 종괴를 보이는 암종으로 입원하였다. 환자는 부분 마취하에 늑막 조직 생검을 받고 침윤성 흉선종의 의심하에 우 전늑막 및 우전폐 절제술을 받았다. 수술중 흉선의 상태는 정상이었으며 폐 첨부로부터 횡격막부위까지의 늑막과 폐엽간, 부분적인 폐 침습을 보이고 심낭의 침윤을 보이는 Masaoka 분류 Stage 로 보이는 침윤성 흉선종으로 진단되 었다. 환자는 술후 600의 방사선 조사를받고 술후 8개월인 현재까지 재발의 징후 없이 경과관찰중이다.

Keywords

References

  1. Mediacal Embryology Langman,J.
  2. Am J Surg Pathol v.19 Primary intrapulmonary thymoma. A clinicopathologic and immunohistochemical study of eight cases Moran,C.A.;Suster,S.;Fishback,N.F.;Koss,M.N.
  3. Cancer v.48 Follow-up study of the thymomas with special reference to their clinical stages Massoka,A.;Monden,Y.;Nakahara,K.;Tanioka,T.
  4. Cancer v.74 Thymoma. Histologic subclassification is an independent prognostic factor Quintanilla Martinez,L.;Wilkins,E.W.Jr;Choi,N.;Efird,J.;Hug,E.;Harris,N.L.
  5. Virchows Arch [A] v.407 Thymoma and thymic carcinoma : relation of thymoma epithelial cells to the cortical & medullary differentiation of thymoma Marino,M.;Muller Hermelink,H.K.
  6. Cancer v.73 Thymona. Retrospective study of 87 cases Park,H.S.;Shin,D.M.;Lee,J.S.;Komaki,R.;Pollack,A.;Putnam,J.B.;Cox,J.D.;Hong,W.K.
  7. J Thorac Cardiovasc Surg v.103 The surgical treatment of invasive thymoma. Resection with vascular reconstruction Shimizu,N.;Moriyama,S.;Aoe,M.;Nakata,M.;Ando,A.;Teramoto,S.
  8. Ann thorac Surg v.61 Surgical treatment for invasive thymoma. Especially when the superior vena Cava is invaded Yagi,K.;Hirata,T.;Fukuse,T.;Yokomise,H.(et al.)
  9. Korean J Thorac Cardiovasc Surg v.28 Surgical treatment of malignant thymoma Park,S.J.;Yim,S.B.;Zo,J.I.;Shim,Y.M.