The Effect of Phrenic Nerve Paralysis After Pediatric Cardiac Surgery on Postoperative Respiratory Care

소아 심혈관 수술 후 발생한 횡격신경마비가 술후 호흡관리에 미치는 영향

  • 윤태진 (서울대학교 의과대학 흉부외과학교실) ;
  • 이정렬 (서울대학교 의과대학 흉부외과학교실)
  • Published : 1996.10.01

Abstract

From January 1990 through December 1995, 43 patients underwent diaphragmatic plication for the management of phrenic nerve palsy .complicating various pediatric cardiovascular surgery. Their mean age at plication was 11.1 months and sex ratio was 31 males to 12 females. In order of decreasing incidence, the primary cardiovascular procedures included modified Blalock-Taussig shunt (7), total correction for the Tetralogy of Falloff (7), arterial switch operation (6), unifocalization for the pulmonary atresia with VSD (3), modified Fontan operation (3), VSD patch closure (3) and others. The involved sides of diaphragm were right in 17, left in 2) and bilateral in 3. Extensive pericardial resection with electocauterization of resected margin was thought to be the most common cause of phrenic nerve palsy (20). The interval between primary operation and plication ranged from the day of operation to 98 days (median 11 days). The methods of plication were central pleating technique(plication with phrenic nerve branch preservation) in 41, and other technique In 2. 10 patients died after plication (7: early, 3; late), and the causes of death were thought to be unrelated to plication itself. Among the 36 early survivors, extubation or cessation of positive pressure ventilation could be accomplished between 1 and 24 days postoperatively(mean : 4.5). Cumulative follow-up was 92 patient years without major complications. Postoperative follow-up fluoroscopy was performed in 6 patients, and the location and movement of plicated diaphragms were satisfactory in 5 patients. We concluded that diaphragmatic plication with preservation of phrenic n rve branch could lead to cessation of positive pressure ventilation and complete recovery of diaphragmatic function in the long term, unless the phrenic nerve was irreversibly damaged.

1990년 1월부터 1995년 12월가지 43명의 환아가 다양한 심혈관수술로 인해 유발된 횡격막 마비로횡 격막 습벽형성술을 시행 받았다. 환아의 평균연령은 11.1개월이었고, 남녀 비율은 31:12였다. 횡격막 마비의 원인이 된 수술로는 변형 Blalock-Taussig단락술 및 활로씨 4징증의 전교정술이 각각 7례로 가장 많았고, 기타 동맥 전환술 6례, 심실중격결손을 동반한 폐동맥 폐쇄증에서의 unifocalization 및 변형 Fontan수술, 심실중격결손 교정 등이 각각 3례씩이었다. 마비된 부위는 우측이 17례, 좌측이 23례, 양측성이 3례였으며, 원인은 대부분 과도한 심낭 절제 및 심낭 절개면 부위의 전기소작으로 추정되었다. 원인이 된 수술후 횡격막 습벽형성술까지의 기간은 수술 당일로부터 98일까지로 대부분 2주이내에 습 벽형성술이 이루어졌다 수술방법은 2례를 제외하고 모두 횡격막 신경분지를 피해서 횡격막을 접어주는 central pleating technique 이 적용되었다. 10명의 환아가 습벽형성술후 사망했으며(조기: 7, 만기: 3), 사망원인은 전례 에서 습벽 형성술과는 무관한 것으로 사료되 었다. 36명의 조기생존자들은 습벽 형성술후 1일에서 24일 사이에 양압호\ulcorner으로 부터 벗어날 수 있었다(평균 4.5일). 6명의 환아가 습벽 형성술후 8개 월에서 52개월 사이에 fluoroscopy를 시행하였으며, 대부분 횡격막의 위치 및 운동성이 양호하였다. 결 론적으로 불가역적인 횡격막 신경 손상이 없다면 횡격막 습벽형성술은 단기적으로는 환아의 양압호흡 의존기 간을 단축시키고 장기적으로는 횡격막 기능의 완전회복을 유도할 수 있다.

Keywords

References

  1. Ann Thorac Surg v.32 Aggressive treatment of acquired phrenic nerve paralysis in infants and small children Shoemaker,R.;Palmer,G.;Brown,J.W.;Kin,H.
  2. Chest v.107 Effects of diaphragmatic pliction on respiratory mechanics in dogs with unilateral and bilateral phrenic nerve paralyses Shin-ichi T.;Kazuya,N.;Yoshitaka,F.(et al.)
  3. Am J Surg v.132 Injuries to the phrenic nerve resulting in diaphragmatic paralysis with special reference to stretch trauma Iverson,L.I.G.;Mittal,A.;Dugan,D.J.;Samson,P.C.
  4. J Thorac Cardiovasc Surg v.94 Phrenic nerve paralysis after pediatric cardiac surgery Watanabe,T.;Trusler,G.A.;Williams,W.G.(et al.)
  5. Ann Thorac Surg v.23 Topical hypothermia and phrenic nerve injury Marco,J.D.;Harn,J.W.;Barner,H.B.
  6. J Thorac Cardiovasc Surg v.89 Phrenic nerve paresis associated with the use of iced slush and cooling jarket for topical hypothermia Rousou,J.A.;Parker,T.;Engelman,R.M.;Breyer,R.M.
  7. J Parenter Enteral Nutr v.12 Neurologic complication of central venous cannulation Defalque,R.J.;Flether,M.V.
  8. J Oral Maxillofac Surg v.46 Paralysis of the hemidiaphragm as a complication of internal jugular vein cannulation : report of a case Hadeed,H.A.;Braun,T.W.
  9. J Thorac Cardiovasc Surg v.109 Midline one-stage complete unifocalization and repair of pulmonary atresia with ventricular septal defect and major aortopulmonary collaterals Reddy,V.M.;Liddicoat,J.R.;Hanley,F.L.
  10. Ann Thorac Surg v.53 Isolated Lung Transplantation for end-stage lung disease : A viable therapy Egan,T.M.;Westerman,J.M.;Lanbert,C.J.(et al.)
  11. Ann Thorac Surg v.58 Plication of paralyzed hemidiaphragm after sleeve pneumonectomy Takeda,S.;Nakahara,K.;Fujji,Y.;Minami,M.;Matsuda,H.
  12. J Pediatric Surg v.14 Management of diaphragmatic paralysis in infants with special emphasis of selection of patients for operative plication Maller,J.A.Jr.;Pickard,L.R.;Tepas,J.J.(et al.)
  13. Br Heart J v.67 Negative extrahoracic pressure ventilation for phrenic nerve palsy after pediatric cardiac surgery Raine,J.;Samvels,M.P.;Mok,Q.;Shinebourne,E.A.;Southall,D.P.
  14. J Pediatric Surg v.13 Plication of the diaphragm for symptomatic phrenic nerve paralysis Schwartz,M.Z.;Filler,R.M.
  15. 대흉외지 v.25 소아 심혈관 수술 후의 횡격막 마비 윤태진;김기봉;이정상(등)
  16. Eur J Cardio-thorac Surg v.6 Plication of the diaphragm for unilateral eventration or paralysis Ribert,M.;Linder,J.L.
  17. J Pediatr Surg v.28 The Long-term results of diaphragmatic plication Kizilcan,F.;Tanyel,F.C.;Hicsonmez,A.(et al.)