Journal of Photoscience

Korean Society of Photoscience (한국광과학회)
권호 표지

THE NEW FINDING OF A LIGHT DEPENDENT $Ca^{2+}$ CHANNEL AND $Na^+-Ca^{2+}$ EXCHANGER IN THE VERTEBRATE RETINA (II)

  • Kim, Yun-Sook (Department of Biochemistry, College of Natural Sciences Kyungpook National University) ;
  • Jung, Hyuk (Department of Biochemistry, College of Natural Sciences Kyungpook National University) ;
  • Park, Chang-Suck (Department of Biochemistry, College of Natural Sciences Kyungpook National University) ;
  • Woo, Suk-Hyang (Department of Biochemistry, College of Natural Sciences Kyungpook National University) ;
  • Kim, Hyun-Jung (Department of Biochemistry, College of Natural Sciences Kyungpook National University) ;
  • Kim, You-Young (Department of Biochemistry, College of Natural Sciences Kyungpook National University)
  • Published : 1996.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

Calcium modulates the activity of guanylate cyclase and plays a key role in dark and light adaptation in the visual system. We have measured the Ca$^{2+}$, K$^+$ and Na$^+$ concentration in dark and light adapted bullfrog's (Rana catesbeiana) vitreous humor by using the atomic absorption spectrophotometer. The calcium concentration of the light adapted bullfrog's vitreous humor was higher than that of the dark adapted bullfrog's vitreous humor. This means that ion activity between the photoreceptor and vitreous humor side is light dependent and we have found that a Ca$^{2+}$ channel and Na$^+$ - Ca$^{2+}$ exchanger exist in the vitreous humor.

Keywords

References

  1. J. Physiol. v.242 Changes in time scale and sensitivity in turtle photoreceptors. Baylor, D. A.;A. L. Hodgkin
  2. J. Physiol. v.261 Sensotivity of toad rods: Dependence on wave length and background illumination. Fain, G. L.
  3. J. Physiol. v.297 Light adaptation in toad rods: Requirement for an internal messenger which is not calcium. Bastian, B.;G. L. Fain
  4. J. Physiol. v.319 Spatial spread of activation and background desensetization in toad rod outer segment. Lamb, T. D.;P. A. McNaughton;K. W. Yau
  5. Nature. v.313 Light-induced erduction of cytoplasnic free calcium in retinal rod outer segment. Yau, K. W.;K. Nakatani
  6. Proc. Nat. Acad. Sci. U.S.A. v.83 Role of calcium in regulating the cyclic GMP cascade of photoransduction in retinal rods. Torre, V.;H. R. Matthews; T. d. Lamb
  7. J. Physiol. v.343 Ionic movements through light sensitive channels of toad rods. Capovilla, M.;A. Caretta;L. Cervetto;V. Torre
  8. Nature. v.309 Cation selectivity of light-sensitive conductance in retinal rods. Yan, K. W.;K. Nakatani
  9. J. Physiol. v.358 The ionic selectivity and calcium dependence of the light-sensitive pathway in toad rods. Hldgkin, A. L.;P. A. McNaughton;B. J. Nunn
  10. J. Physiol. v.391 Measurement of sodium-calcium exchange in salamander rods. Hldgkin, A. L.;P. A. McNaughton;B. J. Nunn
  11. Proc. Nat. Acad. Sci. U.S.A. v.85 Ion transport by Na-Ca exchange in isolated rod outer segment. Lagnado, L.;L. Cervetto;P. A. McNaughton
  12. Review of Medical Physiology(6th ed.) Ganong, W. F.