Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Regioselective synthesis of .alpha.-L-fucosyl-containing benzyl disaccharides by use of .alpha.-L-fucosidases of aspergillus niger

  • Published : 1996.08.01
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Abstract

The activity of fucosidase shows different value depending on disease, eg) fucosidosis and I cell disease are characterized by the absence or deficiences of .alpha.-fucosidase, and sera of ovarian cancer patients exhibited a statistically significant deficiency of .alpha.-L-fucosidase activity (Zielke et al., 1972; Kress et al., 1980; Barlow et al., 1981). For the purpose of diagnosis of these disease easily, the manual of test can be developed by preparing kits of hydrophobic-binding substrate of fucosidase that bind C18-column.

Keywords

References

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