Archives of Pharmacal Research
- 제19권2호
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- Pages.153-159
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- 1996
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
A New Streptothricin Family Antibiotic Producing Streptomyces Spp. Snus 8810-111 ; Characterization of The Producing Organisms, Fermentation, Isolation, and Structure Elucidation of Antibioitics
- Goo, Yang-Mo (Department of Pharmacy, Seoul National University) ;
- Kim, Ok-Yun (Department of Pharmacy, Seoul National University) ;
- Joe, Young-Ae (Department of Pharmacy, Seoul National University) ;
- Lee, Young-Bok (Department of Pharmacy, Seoul National University) ;
- Ju, Jeongho (Department of Pharmacy, Seoul National University) ;
- Kim, Beom-Beom-Tae (Department of Chemistry, Seoul National University) ;
- Lee, Youn-Young (Department of Chemistry, Seoul National University)
- 발행 : 1996.04.01
초록
A new streptothricin family antibiotic producing Streptomyces spp. SNUS 8810-111 was isolated from a soil sample. Study of its morphological and physiological characters indicated that the antibiotic producing organism was a Streptomyces spp. Taxonomical studies suggested that the organism might belong to the genus streptomyces gougeroti. The organism produced antibiotics most in calcium carbonate-tryptic soy broth. The active principles were recovered from the broth with a cation exchange resin and eluted from the resin with HCI. Cellulose column chromatography gave two active principles.
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