Archives of Pharmacal Research
- Volume 19 Issue 5
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- Pages.416-422
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- 1996
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Antitumor Activity of Arylacetylshikonin Analogues
- Kim, Seon-Hee (College of Pharmacy, Chungnam National University) ;
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Song, Gyu-Yong
(College of Pharmacy, Chungnam National University) ;
- Jin, Guang-Zhu (Department of Pharmacy, College of Medicine, University of Yanbian) ;
- Ahn, Byung-Zun (college of Pharmacy, Chungnam National University)
- Published : 1996.10.01
Abstract
Twenty one phenylacetylshikonin analogues were synthesized from various subsitituted phenyl acetic acids and their cytotoxicity values against A549, K562 and L1210 cell lines and antitumor action in mice bearing S-180 cells were measured. All of phenylacetylshikonin analogues expressed a potent cytotoxicity