The Radioprotective Effect of Panax ginseng of the Hair Medullary Cell in Irradiated Mice

방사선 피폭 마우스의 털 수질세포에 대한 인삼의 방사선 방호효과

  • 김성호 (전남대학교 수의과대학) ;
  • 한동운 (전남대학교 수의과대학, 한국원자력연구소 부설 원자력병원)
  • Published : 1996.08.01

Abstract

Studies were Performed to determine whether the water fraction of Panax ginseng Protected radiation damage to hair medullar cells of N:GP(s) mice after in vivo irradiation with $^{60}Co{\;}{\gamma}-rays$. The hair follicles in the middle of the growth cycle were analysed 3 days after 3 Gy irradiation for the changes in the number of cells in the forming medulla of the hair in the region just above the germinal matrix of the growing (anagen) hair follicle. The radioprotective effect of ginseng was compared with the irradiation control. The medullar cell count per unit length ($100{\;}\mu\textrm{m}$) of hair follicle was higher in the pretreated-groups of ginseng, both oral (2 mg/ml of drinking water, p<0.05) and intraperitoneal (0.3 mg/head, p<0.001) treatments, than the irradiation control. These data suggested that the water fraction of Panax ginseng may reduce cell damages on the body surface caused by ${\gamma}-rays$.

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