Journal of Ginseng Research
- Volume 20 Issue 1
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- Pages.106-110
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- 1996
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- 1226-8453(pISSN)
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- 2093-4947(eISSN)
Inhibitory Effects of Ginseng Components on Rat Lens Aldose Reductase Activities
인삼성분의 Rat Lens Aldose Reductase 활성에 대한 억제효과
- Kim, Hack-Seang (College of Pharmacy, Chungbuk National University) ;
- Park, Ung-Yang (College of Pharmacy, Chungbuk National University) ;
- Seong, Yeon-Hee (College of Verterinary, Chungbuk National University)
- Published : 1996.04.01
Abstract
The present study was undertaken to elucidate the effects of ginseng components on rat lens aldose reductase activity. Ginseng total saponin (GTS) exhibited inhibitory activities on rat lens aldose reductase in a dose-dependent manner. Among ginsenosides, Rf and Rgl showed potent inhibitory activities on rat lens aldose reductase. Lipid soluble fraction also inhibited rat lens aldose reductase activities. These data suggest that ginseng components inhibit rat lens aldose reductase activity in vitro.