BMB Reports
- Volume 29 Issue 2
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- Pages.151-155
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- 1996
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- 1976-670X(eISSN)
Effect of Dopamine on a Voltage-Gated Potassium Channel in a Jellyfish Motor Neuron
- Chung, Jun-Mo (Department of Biology, College of Natural Sciences, Ewha Womans University) ;
- Spencer, Andrew N. (Department of Biological Sciences, The University of Alberta)
- Published : 1996.03.31
Abstract
To swimming motor neurons (SMNs) of Polyorchis penicillatus, a hydrozoan medusae, dopamine (DA) acts as an inhibitory neurotransmitter by hyperpolarizing its membrane potential and decreasing its firing rate as well. Such an inhibitory action of DA is caused by an increased permeability to potassium (K) ions. To investigate whether voltage-gated K channels are directly responsible for the membrane hyperpolarization induced by DA, we employed whole-cell voltage clamp configuration. One
Keywords
- catecholamines;
- cnidaria;
- K rectifier;
- voltage-sensitive potassium channel;
- whole-cell voltage clamp