The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Experimental Study on the Effects of Jungchuntang

정천탕(定喘湯)의 효능(效能)에 관한 실험적(實驗的) 연구(硏究)

  • Park, Cheon-Su (Dept. of Oriental Medicine Graduate school of Wonkwang University) ;
  • Han, Sang-Whan (Dept. of Oriental Medicine Graduate school of Wonkwang University)
  • 박천수 (원광대학교 대학원 한의학과) ;
  • 한상환 (원광대학교 대학원 한의학과)
  • Published : 1996.03.30
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Abstract

These studies were carried out to investigate the effect of Jungchuntang water extract on the inhibitory contractile action of acetylcholine in rat. The results of these studies were as follows; 1. Contractile force of acetylcholine from trachea smooth muscle in rat was significantly inhibited by Jungchuntang. 2. Dose-response of acetylcholine pretreated Jungchuntang in rat was not significantly changed. 3. Inhibitory contractile action of acetylcholine pretreated propranolol in rat was decreased. 4. Inhibitory contractile action of acetylcholine pretreated indomethacin was not significantly changed by Jungchuntang. 5. Inhibitory contractile action of acetylcholine pretreated methylene blue was significantly changed by Jungchuntang. 6. Contractile force of acetylcholine from trachea smooth muscle in rat was significantly inhibited by Jungchuntang. 7. Dose-response of acetylcholine pretreated Jungchuntang in rat was not significantly changed. 8. Inhibitory contractile action of acetylcholine pretreated propranolol in rat was decreased. 9. Inhibitory contractile action of acetylcholine pretreated indomethacin was not significantly changed by Jungchuntang. 10. Inhibitory contractile action of acetylcholine pretreated methylene blue was significantly changed by Jungchuntang.

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References

  1. 攝生衆妙方 張時徹
  2. 編註醫學入門(外券二) 李천
  3. 北京中醫學校編 : 漢醫學臨床病理 北京中醫學院
  4. 半瓜丸이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 盧丞錫
  5. 杏子湯不得者宜橘蘇散에 對한 實驗的硏究 韓宗鉉
  6. 五虎湯이 白鼠의 呼吸器系에 미치는 影響 金고淳
  7. 동의내과 증상의 감별과 치료 민순실
  8. 中醫臨床手冊 原安徽中醫學院(編)
  9. 中醫內科學 上海中醫學院(編)
  10. 東醫臨床內科 姜允皓
  11. 實用中醫內科學 上海科學技術出版社
  12. 東醫寶鑑 許浚
  13. 東醫處方大全(1) 東醫科學院
  14. 동의내과학 김규동
  15. 診療要鑑(上) 金定濟
  16. 診療要鑑(下) 金定濟
  17. 國譯景岳全書(六) 張介賓
  18. 圖解常用漢方方劑 許鴻源;許照信(編)
  19. 中醫臨床特講 楡志允
  20. 漢方秘錄 李璟模
  21. 漢方臨床學 裵元植
  22. 中醫內科症狀辨治手冊 方文賢;劉淑淸;初秀君(編)
  23. 辨症診治槪要 白共龍(編)
  24. 中醫治法與方劑 成都中醫學院方劑敎硏組(編)
  25. 中醫師臨床手冊 馬康慈(編)
  26. 古今醫方集成(二) 吳古潛
  27. 中國生草藥硏究發展中心 : 中國方藥學
  28. 赤水玄珠全集(上) 孫東宿(編)
  29. 濟衆新篇 康命吉
  30. 漢方醫學大辭典 中醫大辭典編輯委員會
  31. 醫方考 吳곤
  32. 漢方臨床入門 神戶中醫學硏究會
  33. 壽世保元 공廷賢
  34. 東醫 새 臨床處方集 趙世衡
  35. 對譯證脈 方藥合編 黃度淵
  36. 中醫臨床大全 楊思澍(外)
  37. 病症診治 申天浩
  38. 症狀鑑別治療 李鳳敎
  39. 天眞處方解說 成輔社(編譯)
  40. 診療와 優秀處方 柳基遠
  41. 辨症施治臨床要綱 柳志允;金永坂(編)
  42. 漢藥臨床應用 李尙仁(外)
  43. 臨床本草學 辛民敎
  44. 申氏本草學(各論) 申佶求
  45. 現代本草學 陸昌洙;安德均
  46. 本草綱目 李時珍
  47. 東洋醫學叢書(券4);中藥學 國際韓醫學學生會
  48. 東洋醫學叢書(券4);方劑學 國際韓醫學學生會
  49. 中草藥學 上海中醫學院
  50. 臨床配合本草學 康秉秀;金永坂
  51. 黃帝內經素間靈樞譯解 楊維傑
  52. 淸肺湯 및 加味淸肺湯이 Oleic acid로 誘發시킨 家兎의 肺水腫과 GUINEA PIG의 氣管支平滑筋에 미치는 影響 金炳勳
  53. 紫蘇飮子가 GUINEA PIG의 氣管支平滑筋에 미치는 影響 宋鎭吾
  54. 華蓋散이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 金聖炫
  55. 解表兩陳湯 및 解表二陳湯이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 朴千洙
  56. 麻黃湯이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 洪在義
  57. 九仙散이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 柳東樹
  58. 潤肺除嗽飮이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 尹浩碩
  59. 柴胡枳桔湯이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 李敏燮
  60. 三拗湯 및 神朮散이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 吳英旭
  61. 五拗湯 및 神朮散이 GUINEA PIG의 氣管支平滑筋에 미치는 影響 李始炯
  62. 半夏溫肺湯 및 그 構成藥物이 實驗動物에 미치는 影響 宋鎭吾
  63. 九寶飮이 Sensitized Rat의 氣管支平滑筋에 미치는 影響 李昇祐
  64. 人蔘潤肺散이 Acetylcholine으로 收縮한 Rat의 氣管支平滑筋에 미치는 影響 崔善燁
  65. Physiol. Pflugers Arch, Ges.
  66. Br. J. Pharmac. v.91 The obligatory role of calcium in the delelopment of antigen-induced airway hyper- reactivity to cold provocation in the rat isolated trachea Chand, N.;Diamantis, W.;Sofia, R.D.
  67. Statistical Methods Snedecor, G.H.;Cochran, W.G.
  68. Am. Rev. Respir. Dis. v.118 Bronchial hyperirritability in heathy subjects after exposure to ozone Golden, J.A.;Nadel, J.A.;Boushey, H.A.
  69. Am. Rev. Respir. Dis. v.127 Importance of airway inflamation for hyperresponsiveness induced by ozone Holtzan, M.J.;Fabbri, L.M.;O'Byme, P.M.;Gold, B.D.;Aizawa, H.;Walters, E.H.;Alpert, S.E.;Nadel. J.A.
  70. J. Appl. physiol. v.58 Respiratory epithelium inhibits bronchial smooth muscle tone Flavahan, N.A.;Aarhuus, L.L.;Rimele, T.J.;Vanhoutte, P.M.
  71. J. Appl. physol. v.60 Ozone induced change in bronchial reactivity to methacholine and airway inflammation in humans Seltzer, J.;Bigby, B.G.;Stulbarg, M.;Holtzman, M.J.;Ueki, I.F.;Leikauf, G.D.;Goetzl, E.J.;Boushey, H.A.
  72. Am. Rev. Respir. Dis. v.130 Neutrophil depletion inhibits airway hyperresponsiveness induced by ozone exposure O'Byrne, P.M.;Watlters, E.H.;Gold, B.D.;Aizawa, H.A.;Fabbri, L.M.;Alpert, S.E.;Nadel, J.A.;Holtzman, M.J.
  73. Am. Rev. Respir. Dis. v.130 Indomethacin inhibits the airway hyperresponsiveness but not the neurtrophil influx induce by ozone in dogs O'Byrne, P.M.;Walter, E.H.;Aizawa, H.;Fabbri, L.M.;Holtzman, M.J.;Nadel, J.A.
  74. J. Appl. Physiol. v.59 Leukotriene B4 induced airway hyperresponsiveness in dogs O'Byrne, P.M.;Leikauf, G.D.;Aizawa, H.;Bethel, R.A.;Ueki, I.F.;Holtzman, M.J.;Nadel, J.A.
  75. J. Allergy Clin. Immunol. v.76 The effect of inhaled hexamethonium bromide and atropine sulphate on airway responsiveness to histamine O'Byrne, P.M.;Thomson, N.C.;Latimer, K.M.;Roberts, R.S.;Morris, M.M.;Daniel, E.E.;Hargreave, F.E.
  76. Am. Rev. Respir. Dis. v.134 Inhibition of antigen-induced airway hyperresponsiveness by thromboxane synthetase inhibitor(OKY 046) in allergic dogs Chung, K.F.;Aizawa, H.;Becker, A.B.;Frick, O.;Gold, W.M.;Nadel, J.A.
  77. J. Appl. Physiol. v.65 no.3 Release of epithelium derived relaxing factor after ozone inhalation in dogs Jones, G.L.;Lane, C.G.;Daniel, E.E.;O'Byren, P.M.
  78. Br. J. Pharmacol. v.86 The effect of airway epithelium on smooth muscle contractility in bovine trachea BARNES, P.J.;CUSS, F.M.;PALMER, J.B.
  79. J. Appl. Physiol. v.58 Respiratory epithelium inhibits bronchial smooth muscle tone Flavahan, N.A.;Aarhuus, L.L.;Rimele, T.J.;Vanhoutte, P.M.
  80. Eur. J. Pharmacol. v.129 Airway epithelium modulates the reactivity of guinea-pig respiratory smooth muscle HAY, D.W.P.;FARMER, S.G.;RAEBURN, D.;ROBINSON, V.A.;FLEMING, W.W. FEDAN, J.S.
  81. Mechanisms in Asthma : Pharmacology, Physiology, and Management Neural transmission during ozone-induced airway hyperresponsiveness O'Byrne, P.M.;Jones, G.L.;Lane, C.G.;Pashley, M.;Daniel, E.E.
  82. Eur. J. Pharmacology v.178 The inhibitory influence of tracheal mucosa mounted in close proximity to canine tracheals Manning, P.J.;Jones, G.L.;Otis, J.;Daniel, E.E.;O'Byrne, P.M.
  83. Eur. J. Pharmacol. v.157 B-Adrenoceptor desensitization in guineapig isolated trachea Lynette B. Fernandes;Darryl A. Knight;Paul J. Rigby;Domenico Spina;James W. Paterson;Roy G. Goldie
  84. Pharmacol. Res. Commun. v.18 Arachidonic acid metabolites and lung ${\beta}$-adrenoceptor desensitization Abbrachio, M.P.;Daffonchio, I.;Omini, C.
  85. J. Aulon. Pharma-col v.2 Desensitization of ${\beta}$-adrenoceptor in guinea-pig trachea : A prostaglandin mediated phenomenon Berti. F.L. Daffonchio;Folco, G.C.;Omini, C.;Vigano, T.
  86. Br. J. Pharmacol. v.85 Pharmacological moculation of responses guinea-pig airways contracted with arachidonic acid John F. Burka
  87. Prostaglandins v.22 Immunolgical and nonimmunological synthesis and release of prostaglandines and thromboxanes from isolated guinea pig tracheas Burka, J.F.;Ali, M.;Mcdonald, J.W.D.;Paterson, N.A.M.
  88. Br. J. Pharmac. v.81 Mediators of arachidonic acid -induced contraction of indomethacine-treated guinea pig airways: Leukotrienes C4 and D4 Burka, J.F.;Saad, M.H.
  89. Prostaglandins v.28 Metabolism of arachidonic acid by 5-lipoxygenase in guinea-pig lung Burka, J.F.;Saad, M.H.
  90. Am. Rev. Respir. Dis. v.130 Indomethacin inhibits the airway hyperresponsiveness but not the neutrophil influx by ozone in dogs O'Byrne, P.M.;Walters, E.H.;Aizawa, H.A.;Fabbri, L.M.;Holtzman, M.J.;Nadel, J.A.
  91. Eur. J. Pharmacol. v.136 Demonstration of the release of an epithelium-derived inhibitory fator form a nivel preparation of guinea pig trachea Hay, D.W.P.;Muccitelli, R.M.;Horstemeyer, D.L.;Wilson, K.A.;Raeburn, D.
  92. J. Pharmacol and experimental therapeutics v.232 Selective blockade of endothelium-dependent and gryceryl trinitrate-induced relaxation by hemoglobin and by methylene bule in the rabbit aorta William Martin;Gina M. Villani;Desingaro Jothianandan;Robert F. Furchgott
  93. Res. Commun. Chem. Pathol. pharmacol. v.41 Poasible role for cyclic GMP in endothelium-dependent relaxation of rabbit aorta by acetylcholine. Comparison with nitroglycerin Diamond, J.;Chu, E.B.
  94. Fed. Proc. v.42 Relation of cyclic GMP levels to endothelium-dependent relaxation of rabbit aorta by acetycholine in rabbit aorta (Abstract) Furchgott, R.F.;Jothinandan, D.
  95. Fed. Proc. v.43 Relation of rabbit aorta by light is associated with an increase in cyclic GMP(Abstract) Furchott, R.F.;Jothianandan, D.
  96. J. Cyclic Mucleotide Res. v.8 Endothelium-induced relaxation by acetyl- choline associated with larger rises in cyclic GMP in coronary arterial strips Holzmann, S.
  97. J. Pharmacol. Exp. Ther. v.228 Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery Ignarro, L.J.;Burke, T.M.;Wood, K.S.;Wolin, M.S.;Kadowitz, P.J.
  98. Nature(Lond.) v.306 Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation Rapoport, R.M.;Draznin, M.B.;Murad, F.
  99. Trans. Assoc. Am. Physicans v.96 Endothlium-dependent vasodilator and nitrovasodilator-induced relaxation may be mediated through cyclic GMP formation and cyclic GMP-depeddent protein phosphorylation Rapoport, R.M.;Draznin, M.B.;Murad, F.
  100. 東醫小兒科學 鄭奎萬
  101. 內科學(下) 李文鎬(外)
  102. 東洋醫學大辭典 謝觀