The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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The Effects of Haepyoyijintang on the Pulmonary Injury caused by $SO_2$ in Rats

해표이진탕(解表二陳湯)이 흰쥐의 $SO_2$에 의한 호흡기손상(呼吸器損傷)에 미치는 영향(影響)

  • 이경태 (동의대학교 한의학과 대학원) ;
  • 박동일 (동의대학교 한의학과)
  • Published : 1996.10.30
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Abstract

This experiment was performed in order to study the effects of Haepyoyijintang on the pulmonary injury caused by $SO_2$. Healthy adult male rats weighting about 250g were divided into 4 groups- the Normal group, the Control group, the group of Haepyoyijintang administration for 5 days after $SO_2$ gas exposure (Sample I ), and the group of Haepyoyijintang administration for 10 days before and for 5 days after $SO_2$ gas exposure (SampleⅡ). The results were obtained as follows; 1. In the total number of leucocyte, Sample I and Sample II decreased significantly compared with Control group. 2. In the erythrocyte sedimentation rate, Sample I and Sample Ⅱ decreased significantly compared with Control group. 3. In the lung weight, Sample I and Sample II decreased significantly compared with Control group. 4. In the lung TBA level, only Sample II decreased significantly compared with Control group. 5. In the tracheal glycoprotein level, Sample I and Sample II decreased significantly compared with Control group. According to the above results, Haepyoyijintang has significant effects on the pulmonary injury caused by $SO_2$ in rats.

Keywords

References

  1. 呼吸器學 朴奉植
  2. 成人病豫防 및 管理 李文鎬
  3. 豫防醫學과 公衆保健 豫防醫學과 公衆保健 編纂委員會
  4. 大氣汚染槪論 禹完基
  5. J. Toxicol. Clin. Toxicol. v.29 Air pollutants and the respirtory system, Toxicity and Phamacologic interventions Koenig, J.Q.;Pierson, W.E.
  6. Agents Actions v.26 Sulfur dioxide-induced airway hyperreactivity and pulmonary inflammation in dogs Norris, A.A.;Jackson, D.M.
  7. Japan J. Ind. Health v.4 The effect of sulfur dioxide upon mechanical properities of the lungs in dogs Yokoyama, E.;Ishkawa, K.
  8. Proc. Roy. Soc. Med. v.57 Studies on the Effects of Acute Exposure to Sulfure Dioxide in human Subhects Frank, N.R.
  9. Int. J. Air water Pollution v.8 A Comparison of Effects of $SO_2$ Administred Alond or in Combination with NaCl Particles on Respiratory Mechanics of Healthy Audults Frank, N.R.;Amdur, M.O.;Whittenberger, J.L.
  10. J. Appl. Physiol. v.17 no.252 Effects of Acute Controlled Exposure to $SO_2$ on Respiratory Mechanics of Healthy in Healthy Male Adults Frank, N.R.;Amdur, M.O.;Worcester, J.;Whittenberger, J.L.
  11. Brit. J. Ind. Med. v.23 no.75 A Comparison of Changes in Pulmonary Flow Resistance in Healthy Voluneers Acutely Exposed to $SO_2$ by Mouth and by Nose Frank, N.R.;Speizer, F.E.
  12. Arch. Environ. Health. v.11 no.624 $SO_2$ Effects on the Respiratory System in Dogs Frank, N.R.;Speizer, F.E.
  13. J. Physiol. v.7 no.132 Uptake and Release of $SO_2$ by the Human Nose Frank, N.R.;Speizer, F.E.
  14. J. Allergy. Clin. Immunol. v.76 The effects of sulfur oxides on nasal and lung function in adolescents with extrinsic asthma Koenig, J.Q.;Morgan, M.S.;Horike, M.;Pierson, W.E.
  15. Japan J. Ind. Health v.3 no.77 Effects of $SO_2$ on Human Pulmonary Functions Tomono, Y.
  16. Arch. Environ. Health v.15 no.412 Mechnism of Respiratory Effects During Exposure of Guinea Pigs to Irritants Davis, T.R.A.;Battista, S.P.;Kensler, C.J.
  17. Proc. Roy. Soc. Med. v.57 Studies on the Effects of Acute Exposure to Sulfure Dioxide in human Subjects Frank, N.R.
  18. J. Allergy. Clin. Immunol. v.76 The effects of sulfur oxides on nasal and lung function in adolescents with extrinsic asthma Koenig, J.Q.;Morgan, M.S.;Horike, M.;Pierson, W.E.
  19. Biomed. Pharm. v.44 Respiratory effects of polltion Philip Joet, F.
  20. J. Ind. Hyg. Toxicol. v.4 no.193 The effect of Irritant Gases upon the Rate of Ciliary Activity Cralley, L.V.
  21. Bri. J. Ind. Med. v.13 no.110 Mucous Flow and Cilliary Activity in the Trachea of Rats Exposed to Pulmonary Irritant gas Dalhamn, T.;Rohdin, J.
  22. J. Appl. Physiol. v.20 no.164 Mechanism of Broncoconstriction During Inhalation of Sulfur Dioxide Nadel, J.A.;Salem, H.;Tamplin, B.;Tokwa, Y.
  23. 潤肺膏 및 紫蘇半夏湯과 紫蘇半夏湯加味方의 效能에 關한 實驗的 硏究 崔榮哲
  24. 解表二陳湯의 鎭痛, 鎭痙, 解熱 및 $O_3$ 中毒으로 인한 흰쥐 肺損傷에 미치는 影響 朴東一
  25. 濟衆新編 康明吉
  26. 晴崗醫鑑 金永勳
  27. 東醫寶鑑 許浚
  28. 方藥合編 黃度淵
  29. 淸離滋坎湯 및 淸離滋坎湯加味方이 肺損傷과 免疫機能에 미치는 影響 權顯
  30. 小靑龍湯의 鎭痛，抗痙攣 및 흰쥐의 肺損傷에 미치는 影響 金基昌
  31. 金水六君煎 및 加味鎭咳湯의 效能에 관한 實驗的 硏究 柳尙靑
  32. 解表二陳湯의 鎭痛, 鎭痙, 解熱 및 $O_3$ 中毒으로 인한 흰쥐 肺損傷에 미치는 影響 朴東一
  33. 麻黃杏仁甘草石膏湯이 오존 및 四鹽化炭素로 인한 흰쥐 肺損傷에 미치는 影響 徐成淑
  34. 淸上補下丸이 $O_3$ 및 $CC_{14}$로 인한 白鼠 肺損傷에 미치는 影響 鄭昇杞
  35. 滋陰降火湯 및 滋陰降火湯加味方이 實驗的 肺損傷과 止血에 미치는 影響 鄭熙才
  36. 滋陰降火湯의 滋熱, 鎭痛, 抗痙攣 및 $O_3$ 로 中毒된 白鼠 肺損傷에 미치는 影響 趙然鵬
  37. 蔘蘇飮의 鎭痛, 解熱 및 $O_3$ 中毒으로 인한 흰쥐 肺損傷에 미치는 影響 崔錫鳳
  38. 潤肺膏 및 紫蘇半夏湯과 紫蘇半夏湯加味方의 效能에 關한 實驗的 硏究 崔榮哲
  39. 人蔘黃芪散과 加味鎭咳湯이 $SO_2$에 依한 흰쥐의 呼吸器損傷에 미치는 影響 吳泰煥
  40. 東醫肺系內科學 李珩九;鄭昇杞
  41. Methods Biochem. Anal．II. Winzler, R. J.
  42. 呼吸器學 朴奉植
  43. 成人病豫防 및 管理 李文鎬
  44. 現代環攪衛生學 朴良元;金亨錫
  45. 豫防醫學과 公衆保健 豫防醫學과 公衆保健 編纂委員會
  46. 豫防醫學과 公衆保健 豫防醫學과 公衆保健 編纂委員會
  47. J. Toxicol. Clin. Toxicol. v.29 Air pollutants and the respirtory system, Toxicity and Phamacologic interventions Koenig, J.Q.;Pierson, W.E.
  48. Agents Actions. v.26 Sulfur dioxide-induced airway hyperreactivity and pulmonary inflammation in dogs Norris, A.A.;Jackson, D.M.
  49. Japan J. Ind. Health v.4 no.22 The effect of sulfur dioxide upon mechanical properities of the lungs in dogs Yokoyama, E.;Ishkawa, K.
  50. Proc. Roy. Soc. Med. v.57 Studies on the Effects of Acute Exposure to Sulfure Dioxide in human Subjects Frank, N.R.
  51. Int. J. Air water Pollution v.8 no.125 A Comparison of Effects of $SO_2$ Administred Alone or in Combination with NaCl Particles on Respiratoby Mechanics of Healthy Audults Frank, N.R.;Amdur, M.O.;Whittenberger, J.L.
  52. J. Appl. Physiol. v.17 no.252 Effects of Acute Controlled Exposure to $SO_2$ on Respiratory Mechanics of Healthy in Healthy Male Adults Frank, N.R.;Amdur, M.O.;Worcester, J.;Whitteberger, J.L.
  53. Brit. J. I nd. Med. v.23 no.75 A Comparison of Changes in Pulmonary Flow Resistance in Healthy Voluneers Acutely Exposed to $SO_2$ by Mouth and by Nose Frank, N.R.;Speizer, F.E.
  54. Arch. Environ. Health. v.11 no.624 $SO_2$ Effects on the Respiratory System in Dogs Frank, N.R.;Speizer, F.E.
  55. J. Physiol. v.7 no.132 Uptake and Release of $SO_2$ by the Human Nose Frank, N.R.;Speizer, F.E.
  56. J. Allergy. Clin. Immunol. v.76 The effects of sulfur oxides on nasal and lung function in adolescents with extrinsic asthma Koenig, J.Q.;Morgan, M.S.;Horike, M.;Pierson, W.E.
  57. Japan J. Ind. Health v.3 no.77 Effects of $SO_2$ on Human Pulmonary Functions Tomono, Y.
  58. Arch. Environ. Health. v.15 no.412 Mechnism of Respiratory Effects During Exposure of Guinea Pigs ot Irritants Davis, T.R.A.;Battista, S.P.;Kensler, C.J.
  59. Proc. Roy. Soc. Med. v.57 Studies on the Effects of Acute Exposure to Sulfure Dioxide in human Subjects Frank, N.R.
  60. J. Allergy. Clin. Immunol. v.76 The effects of sulfur oxides on nasal and lung function in adolescents with extrinsic asthma Koenig, J.Q.;Morgan, M.S.;Horike, M.;Pierson, W.E.
  61. Biomed. Pharm. v.44 Respiratory effects of polltion Philip Joet, F.
  62. J. Ind. Hyg. Toxicol. v.4 no.193 The effect of Irritant Gases upon the Rate of Ciliary Activity Cralley, L.V.
  63. Bri. J. Ind. Med. v.13 no.110 Mucous Flow and Cilliary Activity in the Trachea of Rats Exposed to Pulmonary Irritant gas Dalhamn, T.;Rohdin, J.
  64. Japan J. Ind. Health. v.3 no.77 Effects of $SO_2$ on Human Pulmonary Functions Tomono, Y.
  65. J. Appl. Physiol. v.20 no.164 Mechanism of Broncoconstriction During Inhalation of Sulfur Dioxide Nadel, J.A.;Salem, H.;Tamplin, B.;Tokwam Y.
  66. 豫防醫學學會誌 v.3 no.1 亞黃酸가스가 白鼠組織의 Lactic Dehydrogenase Isozyme에 미치는 影響 鄭勇
  67. $SO_2$가 흰쥐의 alkaline phosphatase에 미치는 組織學的 硏究 강용익
  68. 亞黃酸가스가 선조체에 미치는 影響에 관한 組織學的 硏究 박성웅
  69. 急性亞黃酸가스 中毒이 姙娠흰쥐 및 태자간에 미치는 影響에 關한 組織學的 硏究 송인문
  70. J. Allergy Clin. Immunol. v.83 Pulmonary effects of sulfur dioxide exposure and ipratropium bromide pretreatment in adults with non-allegic asthma McManus, M.S.;Koenig, J.Q.;Altman, L.C.;Pierson, W.E.
  71. J. Allergy Clin. Immunol. v.79 The effects of albuterol on sulfur dioxide-induced bronchocon striction in allergic adolescents Koenig, J.Q.;Marshall, S.G.;Horike, M.;Shapiro, G.G.;Furukawa, C.T.;Bierman, C.W.;Pierson, W.E.
  72. 淸上補下丸이 $O_3$ 및 $CCl_4$로 인한 白鼠 肺損傷에 미치는 影響 鄭昇杞
  73. 麻黃杏仁甘草石膏湯이 오존 및 四鹽化 炭素로 인한 흰쥐 肺損傷에 미치는 影響 徐成淑
  74. 蔘蘇飮의 鎭痛, 解熱 및 $O_3$中毒으로 인한 흰쥐 肺損傷에 미치는 影響 崔錫鳳
  75. 小靑龍湯의 鎭痛，抗痙攣 및 흰쥐의 肺損傷에 미치는 影響 金基昌
  76. 滋陰降火湯의 解熱 鎭痛 抗痙攣 및 $O_3$로 中毒된 白鼠 肺損傷에 미치는 影響 趙然鵬
  77. 解表二陳湯의 鎭痛 鎭痙 解熱 및 $O_3$ 中毒으로 인한 흰쥐 肺損傷에 미치는 影響 朴東一
  78. 金水六君煎 및 加味鎭咳湯의 效能에 관한 實驗的 硏究 柳尙靑
  79. 潤肺膏 및 紫蘇半夏湯과 紫蘇半夏湯加味方의 效能에 關한 實驗的 硏究 崔榮哲
  80. 滋陰降火湯 및 滋陰降火湯加味方이 實驗的 肺損傷과 止血에 미치는 影響 鄭熙才
  81. 淸離滋坎湯 및 淸離滋坎湯加味方이 肺損傷과 免疫機能에 미치는 影響 權顯
  82. 人蔘黃芪散과 加味鎭咳湯이 $SO_2$에 依한 흰쥐의 呼吸器損傷에 미치는 影響 吳泰煥
  83. 中國醫學史略 賣得道
  84. 原色臨床本草學 辛民敎
  85. 本草學 李尙仁
  86. 中草藥學 上海中醫學院(編)
  87. 本草綱目 李時珍
  88. 本經疏證 v.1 趨潤安
  89. Casarett and Doull‘S Toxicology John Doull(et al.)
  90. Quart. J. Met. Sec. The cycle of at atmospheric gas-natural and man made Junge, C. E.