Experiment Study on the Anti-Stress of Walgukhwan, Walgukhwan+Ejintang and Walgukhwan+Samultang

월국환(越鞠丸) 및 월국환가미방(越鞠丸加味方)의 항(抗)스트레스 효과(效果)에 관(關)한 실험적(實驗的) 연구(硏究)

  • Ku, Byung-Su (Dept. of Internal Medicine, College of Oriental Medicine, Dong Guk University) ;
  • Lee, Won-Chul (Dept. of Internal Medicine, College of Oriental Medicine, Dong Guk University)
  • 구병수 (동국대학교 한의과대학 내과학교실) ;
  • 이원철 (동국대학교 한의과대학 내과학교실)
  • Published : 1996.04.30

Abstract

This study aimed to evaluate the anti-stress effects of Walgukhwan, Walgukhwan+Ejintang and Wal gukhwan+Samultang. The experimental animals treated with each extracts during 15 days before the immobilization stress. And each experimental animals were endowed with 12 hours immobilization stress. Then the brain, blood and urine catecholamine contents and serum total cholesterol, triglyceride and free fatty acid levels were studied. The result were as followed; 1. Walgukhwan, Walgukhwan+Ejintang and Walgukhwan+Samultang were not statistically effective to the changes of the body weight. 2. Walgukhwan was statistically effective to the increase of the blood norepinephrine content as compared with control. 3. Walgukhwan+Ejintang was statistically effective to the increase of the blood and urine norepinephrine contents as compared with control. 4. Walgukhwan+Samultang was statisticallv effective to the increase of the brain, blood and urine norepinephrine contents and also to the increase of the blood and urine dopamine contents as compared with control. 5. Walgukhwan was statistically effective to the increase of the serum free fatty acid level as compared with control. 6. Walgukhwan+Ejintang was statistically effective to the increase of the serum triglyceride and free fatty acid levels as compared with control. 7. Walgukhwan+Samultang was statistically effective to the increase of the serum total cholesterol, triglyceride and free fatty acid levels as compared with control.

Keywords

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