한국한의학연구원논문집 (Korean Journal of Oriental Medicine)

한국한의학연구원 (Korean Institute of Oriental Medicine)
권호 표지

한약 탕제분획의 항 Herpes simplex virus 활성에 관한 연구

Study on The Anti-HSV (Herpes Simplex Virus) Activity of Korean Traditional Prescriptions (Herb complexes)

  • 강봉주 (한국한의학연구소 기초연구부) ;
  • 고병섭 (한국한의학연구소 기초연구부) ;
  • 양기상 (한국한의학연구소 기초연구부) ;
  • 박갑주 (한국한의학연구소 기초연구부)
  • Kang, Bong-Joo (Department of Basic research, Korea Institute of Oriental Medicine) ;
  • Ko, Byung-Seob (Department of Basic research, Korea Institute of Oriental Medicine) ;
  • Yang, Ki-Sang (Department of Basic research, Korea Institute of Oriental Medicine) ;
  • Park, Kap-Joo (Department of Basic research, Korea Institute of Oriental Medicine)
  • 발행 : 1996.12.30
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초록

Herpes simplex viruses(HSV) are one of the most common infectious virus of man. Though chemotherapies and antibiotics against HSV have been developed in many countries, but anti-HSV agents were not satisfactory to mankind by their toxic reaction and side effects. In order to search for anti-HSV agents from Korean traditional prescriptions, we extended the number of specimens. Both methanol extract and boilling water extract of the Korean traditional prescriptions were screened to detect anti-HSV activities by MTT assay. Korean traditional prescriptions showing anti-HSV activities as methanl extracts were Paekyopsan, Chesupwilyungtang, Yongdamsagantang, and prescription 11. Four methanol extracts showing anti-HSV activities were freationated by hexane and their efficacies were tested. Hexane freationations of Paekyopsan, Chesupwilyungtang, and prescription 11 showed in anti-HSV activities both haxane and methanol fractionation.

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