Korean Journal of Biological Psychiatry (생물정신의학)

The Korean Society of Biological Psychiatry (대한생물정신의학회)
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Circadian Rhythms of Plasma MHPG and HVA Concentrations in Healthy Young Adults

혈장(血漿) MHPG와 HVA 농도(濃度)의 24시간(時間) 주기성(週期性) 변화(變化)에 관한 연구(硏究)

  • Kim, Ki-Woong (Department of Psychiatry, Korea Army II-dong Field Hospital) ;
  • Lee, Jung Hie (Department of Neuropsychiatry, Seoul National University Hospital) ;
  • Woo, Jong Inn (Department of Neuropsychiatry, Seoul National University Hospital)
  • 김기웅 (국군일동병원 정신과) ;
  • 이정희 (서울대학교병원 신경정신과) ;
  • 우종인 (서울대학교병원 신경정신과)
  • Published : 1995.12.25
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Abstract

We invesigated whether the circadian rhythms of plasma MHPG and HVA concentrations exist in 11 healthy young adults, and analyzed the patterns of their circadian rhythms. The results were as follows : 1) The change in the mean plasma MHPG concentrations analyzed by repeated measures ANOVA was not statistically significant. Five subjects showed significant circadian rhythms of plasma MHPG concentrations of each individual, and 4 of those had the acrophases between 17PM and 24PM. 2) The change in the mean plasma HVA concentrations analyzed by repeated measures ANOVA was not statistically significant. Six subjects showed significant circadian rhythms of plasma HVA concentrations of each individual, and 4 of those had the acrophases between 21PM and 6AM. In conclusion, the circadian rhythm pattern of plasma HVA concentrations in our result is consistent with the previous study. It was suggested that plasma MHPG and HVA concentrations should be measured more frequently, and the physical activities of subjects be controlled more strictly for the following study.

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