The Evaluation of the Clinical Features and the Results of Treatment of Localized Head and Neck Malignant Lymphoma

국소성 두경부 악성 임파종의 임상적 특징 및 치료 성적 분석

  • Han Ji-Youn (Department of Internal Medicine, ENT-Head, Catholic University Medical College) ;
  • Choi Byung-Gil (Department of Internal Medicine, Diagnostic radiology, Catholic University of Medical College) ;
  • Kim Min-Sik (Department of Internal Medicine, Neck Surgery, Catholic University Medical College) ;
  • Jang Hong-Seok (Department of Internal Medicine, Therapeutic Radiology, Catholic University Medical College) ;
  • Kim Hoon-Kyo (Department of Internal Medicine, ENT-Head, Catholic University Medical College) ;
  • Hong Young-Sun (Department of Internal Medicine, ENT-Head, Catholic University Medical College) ;
  • Lee Kyung-Shik (Department of Internal Medicine, ENT-Head, Catholic University Medical College) ;
  • Kim Dong-Jip (Department of Internal Medicine, ENT-Head, Catholic University Medical College) ;
  • Park Young-Hak (Department of Internal Medicine, Neck Surgery, Catholic University Medical College) ;
  • Cho Seung-Ho (Department of Internal Medicine, Neck Surgery, Catholic University Medical College) ;
  • Seo Byung-Do (Department of Internal Medicine, Neck Surgery, Catholic University Medical College) ;
  • Yoon Sei-Chul (Department of Internal Medicine, Therapeutic Radiology, Catholic University Medical College) ;
  • Choi Kyu-Ho (Department of Internal Medicine, Diagnostic Radiology, Catholic University Medical College)
  • 한지연 (가톨릭대학교 의과대학 내과학교실) ;
  • 최병길 (가톨릭대학교 의과대학 진단방사선과학교실) ;
  • 김민식 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 장홍석 (가톨릭대학교 의과대학 치료방사선과학교실) ;
  • 김훈교 (가톨릭대학교 의과대학 내과학교실) ;
  • 홍영선 (가톨릭대학교 의과대학 내과학교실) ;
  • 이경식 (가톨릭대학교 의과대학 내과학교실) ;
  • 김동집 (가톨릭대학교 의과대학 내과학교실) ;
  • 박영학 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 조승호 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 서병도 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 윤세철 (가톨릭대학교 의과대학 치료방사선과학교실) ;
  • 최규호 (카톨릭대학교 의과대학 진단방사선과학교실)
  • Published : 1995.06.01

Abstract

Localized non-Hodgkin's lymphomas of head and neck are generally treated with radiation therapy with or without chemotherapy and the results of treatments are favorable, but the recurrences in the primary site or distant sites are a major contributor to failure, We experiened 19 cases of localized non-Hodgkin's lymphomas for 4-year period and retrogradely analized them. We treated patients with Ann Arbor stage I and low grade histology in Working formulation with radiation therapy and patients with Ann Arbor stage II, moderate to high grade histology or extensive tumor size with combination chemotherapy, The complete responses were occurred in 15 of 19 patients (radiation therapy, 5/6 (83.3%); chemotherapy 10/13(76.9%)). 3 relapses were occurred; 2 were in local relapses and 1 was in distant leptomeningeal relapse and the counter-therapeutic modalities were successful in 2 cases. Our results suggest that Ann Arbor stage is significant prognostic factor and appropriate staging with extensive methods is important to improve the results of treatment.

Keywords