The Journal of Dong Guk Oriental Medicine (동국한의학연구소논문집)

  • Volume 4
  • /
  • Pages.313-325
  • /
  • 1995
  • /
  • 1226-556X(pISSN)
Research Institute of Oriental Medicine (동국대학교 한의학연구소)
권호 표지

Effect of Whaganjeon on the hepatoxicity of carbon tetrachloride in rats

화간전(化肝煎)이 carbon tetrachloride로 유도(誘導)한 간중독(肝中毒) 흰쥐에 미치는 영향(影響)

  • Yoo, Jung Won (Dept. of Oriental Prescription, College of Oriental Medicine, Dong Guk Univ.) ;
  • Park, Sun Dong (Dept. of Oriental Prescription, College of Oriental Medicine, Dong Guk Univ.)
  • 유정원 (동국대학교 한의과대학 방제학교실) ;
  • 박선동 (동국대학교 한의과대학 방제학교실)
  • Published : 1995.12.20
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Abstract

The purpose of this study is to observe the effect of Whaganjeon on serum reaction in $CCl_4$ treated rats. In this study, the experimental rats divided four group(Control group, $CCl_4$ group, Whaganjeon group, and Sample group) : Under the same condition, control group were administered water, sample group were administered Whaganjeon for 7days. And then, both $CCl_4$ group and sample group were injected to abdomen with $CCl_4$ for 1days. The change of GOT, GPT, ALP, LDH, and bile acid activity in blood serum. The obtained results are summarised as follows : 1. In the change of SGOT, SGPT contents, as compared with control group, sample group was significantly decreased. 2. In the change of serum ALP contents, as compared with control group, sample group was significantly decreased. 3. In the change of serum bile acid contents, as compared with control group, sample group was significantly decreased. 4. In the change of serum LDH contents, as compared with control group, sample group was significantly decreased.

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