Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

COMPARISON OF PERIPHERAL NERVE REGENERATION FOLLOWING CRUSHING OR RESECTION INJURIES IN RAT SCIATIC NERVES

백서 좌골신경의 압좌상과 절제에 따른 말초신경 재생의 비교

  • Kim, Ho-Seok (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) ;
  • Park, No-Boo (Department of Dentistry, School of Medicine, Keimyung University) ;
  • Kim, Chin-Soo (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
  • 김호석 (경북대학교 치과대학 구강악안면외과학교실) ;
  • 박노부 ;
  • 김진수 (경북대학교 치과대학 구강악안면외과학교실)
  • Published : 1995.03.31
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Abstract

The purpose of this experimental study was to examine and compare the regeneration capacity between crushed nerve & transected nerve. For this study, 20 Sprague-Dawley female albino rats were used as experimental animals and divided into two groups. In group 1, the sciatic nerves were crushed 6mm. in length for 1 min. using maximum force with a needle holder. In group 2, the sciatic nerves were resected 6mm. in length and the gaps were encased by inserting the proximal and distal stumps into each end of silicone tubes. The animals were sacrificed 1 month & 2 months after the experiment. All specimens were fixed in 2.5% glutaraldehyde and 1% Osmium tetroxide solution then embedded in epon 812 and were cross-sectioned at $1{\mu}m.$ After these procedures, specimens were observed under Light microscope. The results obtained were as follows. 1. Group 1 showed greter diameters of regenerating nerves than group 2. 2. Group 1 showed greater number of axons than group 2.

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