Immunoelectron Microscopic Study on the Endocrine Pancreas of the Native Korean Goat: Colocalization of Bovine Pancreatic Polypeptide and Chromogranin

한국재래산양 췌장 내분비세포의 면역전자현미경적 연구 : bovine pancreatic polypeptide와 chromogranin의 공존

Pancreatic endocrine cells of the native Korean goat were investigated immunocytochemically at electron microscopic level. All glucagon-, insulin-, somatostatin- and pancreatic polypeptide(PP)-immunoreactive cells were showed chromogranin(CG) immunoreactivity in the secretory granules of each cells. In addition, bovine pancreatic polypeptide immunoreactivity was found to be colocalized in the secretory granules of the glucagon and insulin cells. These observations support that chromogranin is available as the marker of pancreatic endocrine cells on the native Korean goat and BPP colocalized in the secretory granules of glucagon and insulin cells.