Pediatric Infection and Vaccine
- Volume 2 Issue 2
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- Pages.194-199
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- 1995
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- 2384-1079(pISSN)
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- 2384-1087(eISSN)
A Case of Panhypogammaglobulinemia in Patient with Pneumococcal Empyema
폐렴 구균 농흉으로 수술적 치료까지 받은 범저감마글로불린혈증 1례
- Choi, Jae Won (Department of Pediatrics, Kyunghee University) ;
- Oh, Seung Jung (Department of Pediatrics, Kyunghee University) ;
-
Cho, Byung Soo
(Department of Pediatrics, Kyunghee University) ;
- Cha, Sung Ho (Department of Pediatrics, Kyunghee University) ;
-
Choi, Yong Mook
(Department of Pediatrics, Kyunghee University)
- 최재원 (경희대학교 의과대학 소아과학교실) ;
- 오승정 (경희대학교 의과대학 소아과학교실) ;
-
조병수
(경희대학교 의과대학 소아과학교실) ;
- 차성호 (경희대학교 의과대학 소아과학교실) ;
-
최용묵
(경희대학교 의과대학 소아과학교실)
- Published : 1995.11.25
Abstract
Most boys afflicted with panhypogammaglobulinemia, also known as X-linked agammaglobulinemia, remain healthy during the first 6 to 12 months of life because of protection by maternally transmitted IgG antibodies. Thereafter, they repeatedly acquire infections with high-grade pathogens, such as pneumococci, streptococci, and hemophilus unless given antibiotics or immunoglobulin replacement therapy. We experienced a case of panhypogammaglobulinemia in a 4 years old boy. He had been suffered from recurrent upper respiratory tract infection, otitis media and pneumonia since late infancy. He was admitted due to right pleural effusion with pneumonia, and streptococcus pneumoniae was isolated from pleural fluid and blood cultures. His immune status revealed panhypogammaglobulinemia and deficiency in mature B lymphocyte. He was treated with appropriate antibiotics therapy, but showed poor responses. He was transferred to department of thoracic surgery, and received minithoracotomy (decortication) operation. He was successfully treated with operation, antibiotics, and IV gammaglobulin infusions. Now he is being followed with periodic IV gammaglobulin replacement therapy.