Synthesis of New Morindaparvin A Derivatives (Ⅱ)

새로운 Morindaparvin A 유도체들의 합성 (Ⅱ)

  • Park, Si Ho (Department of Chemistry, Chonbuk National University) ;
  • Rho, Young S. (Department of Chemistry, Chonbuk National University) ;
  • Kwon, Yoon Ja (Department of Chemistry, Chonbuk National University) ;
  • Kang, Heun Soo (Research & Development Center of Miwon co., LTD.) ;
  • Cho, In Ho (Department of Chemistry, Chonbuk National University)
  • 박시호 (전북대학교 자연과학대학 화학과) ;
  • 로영쇠 (전북대학교 자연과학대학 화학과) ;
  • 권윤자 (전북대학교 자연과학대학 화학과) ;
  • 강흔수 (미원중앙연구소 제3연구실) ;
  • 조인호 (전북대학교 자연과학대학 화학과)
  • Published : 19950300

Abstract

A simple and efficient synthesis of new kind of Morindaparvin A derivatives (2~8) containing $-N(CH_3)_2,\;-OMe,\;-NH_2,\;-COOH,\;-CHClC(O)NH_2,\;-CHClCH_2OH\;and\;-CHClC(O)CH_3$ was completed with the reported 1,2-dihydroxyanthraquinone derivatives (9, 10).

이미 합성하여 보고한 1,2-Dihydroxyanthraquinone 유도체(9, 10)에 매우 간편하고 효율적인 방법으로 $-N(CH_3)_2,\;-OMe,\;-NH_2,\;-COOH,\;-CHClC(O)NH_2,\;-CHClCH_2OH,\;-CHClC(O)CH_3$ 등이 붙은 여러 종류의 새로운 Morindaparvin A(2~8)의 유도체를 합성하였다.

Keywords

References

  1. J. Nat. Prod. v.45 Chang, P.;Lee, K. H.;Shingu, T.;Hirayama, T.;Hall, I. H.
  2. Photochemistry v.23 Chang, P.;Lee, K. H.
  3. J. Nat. Prod. v.48 Chang, P.;Lee, K. P.
  4. J. Nat. Prod. v.52 Khanapure, S. P.;Biehl, E. R.
  5. Bull. Kor. Chem. Soc. v.15 Rho, Y. S.;Park, S. H.;Kim, S. Y.;Yun, Y. K.;Cho, I. H.
  6. Can. J. Chem. v.50 Hanessian, S.;Moralioglu, E.
  7. Ann v.1 Meerwein, H.;Florian, H.;Schon, N.;Stopp, G.
  8. Tetrahedron Lett. v.8 Hanessian, S.;Bargiotti, A.;LaRue, M.
  9. Tetrahedron v.38 Camps, P.;Cardellach, J.;Font, J.;Ortuno, R. M.;Ponsati, O.
  10. Syn. Kume, A.;Tanimura, H.;Nishiyama, S. I.;Sekine, M.;Hata, T.
  11. Tetrahedron Lett. v.31 Vanhessche, K.;Eycken, E. V.;Vandewalle, M.;Roper, H.
  12. Synlett Bestmann, H. J.;Roth, D.
  13. Synlett Hudlicky, T.;Price, J. D.
  14. Syn. Taylor, E. C.;Chiang, C. S.
  15. Syn. Patwardhan, S. A.;Dev, S.
  16. Tetrahedron v.23 Jarman, M.;Reese, C. B.;Sulston, J. E.
  17. Syn. Cabidu, S.;Melis, S.
  18. Chem. Ber. v.98 Eckstein, F.;Cramer, F.
  19. J. Chem. Soc. Chem. Commun. Bonthrone, W.;Cornforth, J. W.
  20. J. Chem. Soc., Chem. Commun. Clark, J. H.;Miller, J. M.
  21. Tetrahedron Lett. v.38 Clark, J. H.;Holland, H. L.;Miller, J. M.
  22. Tetrahedron v.28 Graefe, J.;Bayerl, B.;Kleinpeter, E.;Muhlstadt, M.
  23. Hel. Chem. Acta Bosshard, H. H.;Mary, R.;Schmid, M.;Zollinger, H.
  24. J. Org. Chem. v.37 Walborsky, H. M.;Niznik, G. E.
  25. Angew. Chem. v.72 Eilingsfeld, H.;Seefelder, M.;Weidinger, H.
  26. Org. Syn. Coll. Ⅳ Hall, L. A. R.;Stephens, V. C.;Burckhalter, J. H.
  27. Tetrahedron Lett. v.41 Ege, G.;Frey, H. O.