참고문헌
- J. Pharmacol. Meth. v.13 McPherson, G. A.
- J. Pharmacochem. Libr. v.10 Schaper, K.
- SYBYL 6.0 Manual
- J. Med. Chem. v.16 Fuller, R. W.;Molloy, B. B.;Day, W. A.;Roush, B. W.;Marsh, M. M.
Bulletin of the Korean Chemical Society
- 제16권2호
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- Pages.110-112
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- 1995
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- 0253-2964(pISSN)
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- 1229-5949(eISSN)
DOI QR Code
Modified LOGIT(MLOGIT) Transformation: Prediction of $IC_{50}$ Value from Two Arbitrary Concentration Data
초록
A LOGIT transformation is a method to estimate IC50 values with two arbitrary concentration data when complete dose response curves(DRCs) are not available. We propose a modified LOGIT transformation (MLOGIT) which predicts IC50 values more accurately than the conventional LOGIT method.
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