Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Antiviral Effect of Lithium-Ascorbate Derivatives

아스코르빈산-리듐 유도체의 바이러스에 대한 불활성화 작용

  • Kil-Jin Kang (Dept. of Food Science and Technology, and Institute of Agriculture Science & Technology, Chonnam National University) ;
  • Akira Murata (Dept. of Applied Biological Science, Saga University)
  • Published : 1995.06.01
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Abstract

The effect of lithium-ascorbate derivatives on viruses was investigated using a wide variety of bacterial viruses(phage). Lithium-ascorbate derivatives exerted an inactivating effect on all phages examined. Lithium-ascorbate derivatives have antiviral effects. The antiviral effect of lithium 2-o-octadecyl ascorbate was stronger than that of lithium ascorbate. Even at 10∼20 times lower concentration, the lithium 2-o-octadecyl ascorbate showed very much similar phage inactivating effect to that of ascorbate and lithium ascorbate.

아스코르빈산-리듐 유도체의 항바이러스의 작용을 검토하기 위하여 여러 종의 박테리아 파이지를 이용하여 이에 대한 불활성화를 조사하였다.아르코르빈산-리듐 유도체는 조사된 모든 파야지에 대하여 불활성화를 보이므로서 항바이러스 작용이 있음을 알 수 있었다. Lithium 2-o-octadecyl ascorbate의 파야지 불활성화 작용은 lithium ascorbate와 아스코르빈산 보다 10~20배 정도 강하였다. 이러한 결과들은 아스코르빈산-리듐 유도체도 아스코르빈산과 마찬가지로 항바이러스 작용이 있으며 그 정도는 아르코르빈산과 비슷하거나 또는 좀 더 강함을 보여 주었다.

Keywords

References

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