한국미생물·생명공학회지 (Microbiology and Biotechnology Letters)

  • 제23권5호
  • /
  • Pages.565-572
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  • 1995
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  • 1598-642X(pISSN)
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  • 2234-7305(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
권호 표지

Cathepsin B 저해물질을 생산하는 Streptomyces chromofuscus의 분리 및 동정

Isolation and Identification of Streptomyces chromofuscus Producing Cathepsin B Inhibitor

  • 발행 : 1995.10.01
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초록

The aim of the present research program was to develop a strain of actinomycetes producing extracellular cathepsin B inhibitor. Soil samples were collected from various sites in Korea and a number of actinomycetes were isolated from the soil samples by applying various physical and chemical pretreatments. An economical and effective method was developed for the screening of strains producing low molecular weight cathepsin B inhibitor, and consequently a strain (SMF28) among over 700 isolates was selected. Chemotaxonomic and numerical identification were carried out for the isolate. Fifty taxonomic unit characters were tested and the data were analyzed numerically using TAXON program. The isolate was identified as a strain of Streptomyces chromofuscus.

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참고문헌

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