Journal of Life Science (생명과학회지)
- Volume 5 Issue 1
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- Pages.26-32
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- 1995
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- 1225-9918(pISSN)
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- 2287-3406(eISSN)
Antimutagenic Effect of Insoluble Dietary Fibers from Some Green Yellow Vegatagles and Soybean by Binding the Carcinogens
녹황색채소류 및 대두에서 분리한 불용성 식이섬유의 항돌연변이 효과
- Lee, Seon-Mi ;
- Rhee, Sook-Hee ;
- Park, Kun-Young ;
- Rh-ew, Tae-Hyong ;
-
Kim, Byeong-Gee
;
-
Chung, Hae-Young
- 이선미 (부산대학교 식품영양학과) ;
- 이숙희 (부산대학교 식품영양학과) ;
- 박건영 (부산대학교 식품영양학과) ;
- 류태형 (부산대학교 생물학과) ;
-
김병기
(부산대학교 생물학과) ;
-
정해영
(부산대학교 약학과)
- Published : 1995.02.01
Abstract
The antimutagenic effects of insoluble dietary fibers(IDF) extracted from some green-yellow vegetables(kale, carrot, spinach, broccoli and soybean sprout) and soybean by binding the carcinogens of MeIQ (2-amino-3,4- dimethyl-imidazo(4,5-f) quinoline) and Trp-P-2(3-amino-1-methyl-5H-pyrido[4,3-b] indole) in Salmonella tylhimirium TA100 and TA98 were studied. All of the insoluble dietary fiber samples which binded MeIQ exhibited high antimutagenic effects by removing the mutagen. Among the samples, IDFs from kale and soybean showed strong binding capacity fo the carcinogen and revealed about 90% of the antimutagenic activity. the IDF samples showed somewhat lower binding capacity to the Trp-p-2. The lignin which extracted from kale, soybean and carrot, and the cellulose strongly removed the mutagenicity of MeIQ by the binding. Among the samples, the level of lignin in kale revealed the highest(about 10%), and it seemed that the higher content of lignin in kale is one of the reasons to increase its antimutagenic effect.