Journal of Chest Surgery

The Korean Society for Thoracic and Cardiovascular Surgery (대한심장혈관흉부외과학회)
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Clinical Results of Double Mitral and Aortic Valve Replacement with the St. Jude Medical Prosthesis

쎈트쥬드 중복판막치환의 장기 임상성적

  • Published : 1995.07.01
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Abstract

A total of and consecutive 87 patients underwent concomitant double mitral and aortic valve replacement with the St. Jude Medical prosthesis between January 1985 and December 1993. They were 44 males and 43 females with the ages ranging from 18 to 59 years[mean$\pm$SD: 40.9$\pm$9.5 years . Fifteen patients[17.2% had a history of previous cardiac valve replacement. There were 2 early deaths[2.3% , and 85 early survivors were followed up for a total of 352.6 patient-years[mean$\pm$SD: 4.1 $\pm$2.6 years . All were anticoagulated with coumadin keeping the target international normalized ratio within the range of 1.5 and 2.5. There was a single late death[late mortality of 0.284%/patient-year . Thromboembolism was the most frequent complication[1.985%/patient-year , and bleeding related to anticoagulation was experienced in one patient [0.284%/patient-year . The incidences of prosthetic valve endocarditis and of paravalvular leak were also low[0.284%/patient-year, respectively . The survival including operative mortality was 96.1%$\pm$2.2% at 10 years. The actuarial probabilities of freedom from thromboembolism and from all events were 77.9%$\pm$11.1% and 72.4%$\pm$10.7%, respectively, at 10 years. There was no structural failure of the prosthesis. Results from a series of clinical studies suggest strongly that the use of lower intensity of anticoagulation therapy lowers the thromboembolic as well as bleeding rates in patients with the ST. Jude Medical prosthesis.

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References

  1. 대흉외지 v.27 승모판막의 장기임상성적 김종환;St.Jude
  2. 대흉외지 v.28 쎈트쥬드 대동맥판막의 장기 임상성적 김종환
  3. J. Thorac Cardiovasc Surg v.96 Guidelines for reporting morbidity and mortality after cardiac valvular operations Edmunds,L.H.Jr.;Clark,R.E.;Cohn,L.H.;Miller,D.C.;Weisel,R.D.
  4. Proceedings of the 1989 Symposium. Surgery for Heart Valve Disease. Aortic,mitral. and multiple valve replacement with the St. Jude Medical device (SJM) at the University Hospital Zurich 1980-1987. Schneider,K.E.;Hofer,M.;Siebenmann,R.(et al.)
  5. Ann Thorac Surg v.47 Ten years' experience with the St. Jude Medical valve prosthesis Arom,K.V.;Nicoloff,D.M.;Kersten,T.E.;Northrup,W.F.Ⅲ.;Lindsay,W.G.;Emery,R.W.
  6. J. Thorac Cardiovasc Surg v.100 Ten-year experience with the St. Jude Medical valve for primary valve replacement Czer,L.S.C.;Chaux,A.;Matloff,J.M.(et al.)
  7. J. Thorac Cardiovasc Surg v.107 Early and latephase events after valve replacement with the St. Jude Medical prosthesis in 1200 patients Fernandez,J.;Laub,G.W.;Adkins,M.S.(et al.)
  8. Ann Thorac Surg v.57 Twelve years' experience with the St. Jude Medical valve prosthesis Nakano,K.;Koyanagi,H.;Hashimoto,A.(et al.)
  9. J Heart Valve Dis v.3 Diagnostic pitfall and the reporting of cerebrovascular events in patients with prosthetic heart valves Sherrington,C.;Bamford,J.
  10. J Heart Valve Dis v.2 Guidelines for prevention of thromboembolic events in valvular heart disease Gohlke-Barwof,C.;Acar,J.;Burckhardt,D.(et al.)
  11. J Heart Valve Dis v.2 German experience with low intensity anticoagulation (GELIA): Protocol of a multi-center randomized, prospective study with the St. Jude Medical valve Hostkotte,D.;Bergemann,R.;Althaus,U.(et al.)
  12. J Heart Valve Dis v.2 Unexpected findings concerning thromboembolic complications and anticoagulation after complete 10 year follower up of patients with St. Jude Medical prostheses Horstkotte,D.;Schulte,H.;Bircks,W.;Strauer,B.
  13. J. Thorac Cardiovasc Surg v.107 Lower intensity anticoagulation therapy results in lower complication rates with the St. Jude Medical prosthesis Horstkotte,D.;Schulte,H.D.;Bircks,W.;Strauer,B.E.