YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Effect of Polysaccharide from Trichosanthes kirilowii on Antidiabetic Activity and Glutathione Metabolism in Hyperglycemic Rats

괄루근으로부터 추출한 다당류의 항당뇨활성 및 당뇨성 쥐의 글루타치온대사에 미치는 영향

  • Published : 1995.10.01
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Abstract

This investigation was aimed at the study of the antidiabetic activity and effect on hepatic glutathione metabolism of polysaccharide from Trichosanthes kirilowii in hyperglycemic rats with aboxan (175 mg/Kg, i.p.). As the results, the polysaccharide inhibited the increase of blood glucose, triglyceride level and lactate dehydrogenase activity, but cholesterol not changed. And it increased protein bound-SH, nonprotein bound-SH, glutathione level and inhibited the decrease of glutathione S-transferase.

Keywords

References

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