YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
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Synthesis of an Intermediate for Carbaprostacyclin: Stereoselective Synthesis of 1-Alkoxy-3-benzenesulfonyl-3-cyano-4-ethenyl cyclopentane

카바프로스타싸이클린 중간체의 합성 : 1-Alkoxy-3-benzenesulfonyl-3-cyano-4-ethenyl cyclopentane의 입체선택적 합성

  • Published : 1995.02.01
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Abstract

An efficient and stereoselective synthetic route to the trisubstituted hydroxy cyclopentane as an useful synthetic intermediate for carbaprostacyclin is described. Pd(0)-mediated intramolecular alkylation of allylic carbonate has been employed as a key reaction.

Keywords

References

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  2. Yakhak Hoeji v.37 Synthesis of Hydroxycyclopentane as a Synthetic Intermediated for Carbaprostacyclin Suh,Y.G;Koo,B.A.;Jung,J.K.;Cho,Y.S.;Lah,W.L.
  3. Chem. Lett. v.63 Facile Synthesis of cis-Fused Carbocycle via Combination of Claisen Rearrangement of Macrolactone and Nitrile Oxide Cycloaddition Suh,Y.G;Kim,S.A.;Cho,H.W.;Cho,Y.S.
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  5. Unpublished results. In Maniscript for publication