Studies on the Synthesis of Protoberberine Related Compounds and its Activities

프로트베르베린 관련화합물 합성 및 활성검토

  • Published : 1995.02.01

Abstract

In order to investigate the biological activity of protoberberine derivatives, they were synthesized four derivatives (1-4) of 7,8 adduct of cycloberberine, two derivatives (5, 6) treated with alkylamine or phenylamine, four compounds (7, 8) and (9, 10) adduct with 1,3-dichloroacetone and oxalychloride. Antibacterial activity of these synthesized compounds was tested.

Keywords

References

  1. Yakhak Hoeji v.38 no.4 Synthesis of 8-methyl-8,14-cycloberbine derivatives S.H.Hwang;J.H.Kim;H.Y.Yim;S.K.Kim
  2. Chem. Pharm. Bull. v.33 Chemical transformation of protoberberines(Ⅶ) M.Hanaoka;S.K.Kim;M.Inoue;K.Nagami;S.Yasuda
  3. Chem. Pharm. Bull. v.35 Chemical transformation of protoberberines(XIV) M.Hanaoka;S.K.Kim;S.I.Sakurai;Y.Sato;C.Mukai
  4. Chem. Pharm. Bull. v.35 Chemical transformation of protoberberines(ⅩI) M.Hanaoka;W.J.Cho;M.Marutoni;C.Mukai
  5. Heterocycles v.19 Ring D inversion of protoberberine alkaloids, conversion of berberine into Non-Naturally occuring 11,12-oxygenated protoberberines M.Inoue;M.Takahasi;M.Hanoka;S.Yasuda
  6. Chem. Pharm. Bull. v.32 no.6 Chemical transformation of protoberberines(Ⅴ) M.Hanaoka;C.Mukai;K.Nagami;K.Kajima;S.Yasuda
  7. Tetrahedron Letters v.39 Photo chemical Valence tautomerization of berberinephenolbetaines to 8,14-cycloberbines, Versatile aziridine derivatives for spirobenzyl isoquinolines M.Hanoka;S.Yasuda;K.nagami;K.Okazima;T.Imanish
  8. Chem. Pharm. Bull. v.36 no.9 A convenient transformation of spirobenzy-lisoquinolines to dehydrophthalide isoquinolines M.Hanaoka;T.Mitsuoka;S.Yasuda;S.K.Kim
  9. Heterocycles v.22 A total synthesis of(±)-Corydaline from coptisine M.Hanaoka;S.Ashimori;S.Yasuda
  10. Chem. Pharm. Bull. v.33 no.4 Reaction of 4-Aroylquinazolines with Sodium hydroxide T.Higashino;M.takemoto;E.Hayash
  11. J. Nat. Prod v.47 no.1 The benzophen anthridine alkaloids B.D.Kran;M.O.Fagbule;M.Shamma;B.Gozler
  12. Tetrahedron Letters v.26 no.7 A highly Stereosec letive of (±)-dihydrofumariline-1 M.Hanaoka;M.Iwasaki;C.Mukai
  13. These collection, Kyung Hee Univ. v.18 Studies on the synthesis of benzo phenanthridine alkaloid from berberine K.K.Lee;N.J.Kim;S.K.Kim
  14. Yakhak Hoeji v.36 no.11 Synthesis of protoberberine derivativers and their biological activies S.K.Kim;C.H.Kwon;C.S.Yook;Y.S.Rho;S.H.Seo;S.Y.Choung;S.H.Chung;D.H.Kim;S.H.Hwang
  15. Yakhak Hoeji v.38 no.1 Synthesis of protoberberine related compound and their Antifungal activities S.K.Kim;D.H.Kim;K.H.Chung;S.H.Hwang;J.H.Kim