Archives of Pharmacal Research
- Volume 18 Issue 1
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- Pages.51-55
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- 1995
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis of Some new 2-Azolyl-and Azinylthiopyrimidines
- Sherif, Laila-Abrahim (National Organization of Drug Control and Research) ;
- Sherif, Sherif-M. (Department of Chemistry, Faculty of Science, University of Cairo) ;
- Rasha-A.M. Faty (Department of Chemistry, Faculty of Science, University of Cairo) ;
- Fattah, Abdel-Samei-M. Abdel (Department of Chemistry, Faculty of Science, University of Cairo)
- Published : 1995.02.01
Abstract
A facile convenient syntheses of the titled compounds, via reacting the precusor 2-amino-2-(pentane-2, 4-dion-3-yithio)-6-phenylpyrimidine-5-carbonitrile (1) with nitrogen nucleophiles and with the carbanions of some active methylene compounds, is reported. Chemical and spectroscopic evidence of the newly syntheised compounds are described.