BMB Reports
- 제28권4호
- /
- Pages.290-292
- /
- 1995
- /
- 1976-670X(eISSN)
Hydrophobic Interaction Between the Acyl Moiety of Choline Esters and the Active Site of Acetylcholinesterase
- Myung, Pyung-Keun (Department of Pharmacy, College of Pharmacy, Chungnam National University) ;
- Sok, Dai-Eun (ARTC #6-7, Agency for Defense Development)
- 발행 : 1995.07.31
초록
Existence of a binding site for choline esters with an acyl chain of various sizes was examined by comparing the inhibitory potency of the respective compound. In contrast to acetylcholine, which showed a pure competitive pattern of inhibition, choline esters with an acyl chain of a long size (