대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지

청금음(淸金飮)이 GUINEA PIG의 기관지(氣管支) 평골근(平滑筋)에 미치는 영향(影響)

Effect of Chunggeumeum Extract on The Contraction of Isolated Guinea Pig Trachea Smooth Muscle

  • 이철현 (원광대학교 대학원 한의학과) ;
  • 한상환 (원광대학교 대학원 한의학과)
  • Lee, Cheol-Hyeon (Dept. of Oriental Medicine Graduate school of Won Kwang University) ;
  • Han, Sang-Whan (Dept. of Oriental Medicine Graduate school of Won Kwang University)
  • 발행 : 1995.06.30
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초록

These studies were carried out to investigate the effect of Chunggeumeum water extract on the inhibitory contractile action of acetylcholine in guinea pig. The results of these studies were as follows; 1. Contractile force of acetylcholine from trachea smooth muscle in guinea pig was significantly inhibited by Chunggeumeum. 2. Dose-response of acetylcholine pretreated Chunggeumeum in guina pig was not significantly changed. 3. Inhibitory contractile action of acetylcholine pretreated propranolol in guinea pig was decreased. 4. Inhibitory contractile action of acetylcholine pretreated indomethacin was not significantly changed by Chunggeumeum. 5. Inhibitory contractile action of acetylcholine pretreated methylene blue was not significantly changed by Chunggeumeum.

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