Korean Journal of Pharmacognosy (생약학회지)
- Volume 26 Issue 4
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- Pages.323-326
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- 1995
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Isolation of Antitumor Agent from the Heartwood of Dalbergia odorifera
강진향(降眞香)의 항암활성 성분
-
Park, Jong-Dae
(Korea Ginseng & Tobacco Research Institute)
;
- Lee, You-Hui (Korea Ginseng & Tobacco Research Institute) ;
-
Baek, Nam-In
(Korea Ginseng & Tobacco Research Institute)
;
- Kim, Shin-Il (Korea Ginseng & Tobacco Research Institute) ;
- Ahn, Byung-Zun (College of Pharmacy, Chungnam National University)
- Published : 1995.12.30
Abstract
Through bioassay-guided separation of the chemical constituents from the heartwood of Dalbergia odorifera, an 2'-O-methoxyisoliquiritigenin(1) was isolated as cytotoxic principle. 1 showed potent cytotoxic activity against the three kinds of human cancer cell lines (A-549, SK-MEL-2 and SK-OV-3) with similar activity to 5-Fluorouracil.
Keywords