Effects of the Fractions from the Leaves, Fruits, Stems and Roots of Cudrania tricuspidata and Flavonoids on Lipid Peroxidation

꾸지뽕나무 잎, 열매, 줄기 및 뿌리의 분획물 과 플라보노이드 화합물이 흰쥐의 과산화지질 함량에 미치는 영향

We studied the effects of the methanolic extracts and fractions from leaves, fruits, stems and roots of Curadrania tricuspidata on the formation of lipid peroxide. The methanol extracts of leaves, fructus and stem of this plants decreased the formation of lipid peroxide in the isolated rat liver. The ethyl acetate fraction of leaves and n-butanol fraction of stems reduced the lipid peroxide formation. It showed that arthocarpesin, one of the constituents isolated from this plant, lowered the formation of lipic peroxide by 13%, 21%, 22% and 25% at the concentration of $10^{-8},\;10^{-6},\;10^{-4}\;and\;10^{-2}mg/ml$, respectively.