Korean Journal of Pharmacognosy (생약학회지)
- Volume 26 Issue 1
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- Pages.57-61
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- 1995
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Effects of Herbal Medicines on Catecholamine Biosynthesis in PC12 Cells
수종의 생약이 PC12 Cells 중의 Catecholamines 생합성에 미치는 영향
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Lee, Myung-Koo
(College of Pharmacy, Chungbuk National University) ;
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Hwang, Bang-Yeon
(College of Pharmacy, Chungbuk National University) ;
- Jung, Eun-Hee (Department of Home Economics Education, Seowon University) ;
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Lee, Kyong-Soon
(College of Pharmacy, Chungbuk National University) ;
- Kim, Hack-Seang (College of Pharmacy, Chungbuk National University)
- Published : 1995.03.30
Abstract
MeOH extracts of eight herbal medicines were investigated for the effects on catecholamine biosynthesis and tyrosine hydroxylase (TH) activity in PC12 cells. Among them, the MeOH extracts of Polygalae Radix and Rehmaniae Radix showed 32 and 22% inhibition on the dopamine biosynthesis, respectively at a concentration of