Natural Product Sciences
- 제1권1호
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- Pages.55-60
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- 1995
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- 1226-3907(pISSN)
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- 2288-9027(eISSN)
Isolation of Ethanol Metabolizing Enzyme Inhibitors from Aloe spp.
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Shin, Kuk-Hyun
(Natural Products Research Institute, Seoul National University) ;
- Woo, Won-Sick (Natural Products Research Institute, Seoul National University) ;
- Chung, Ha-Sook (Natural Products Research Institute, Seoul National University) ;
- Shim, Chang-Sub (R & D Center, Kim Jeong Moon Aloe Co., Ltd.)
- 발행 : 1995.12.01
초록
In the course of evaluation of hepatoprotective components against alcohol-induced toxicity from Aloe spp., the methanol extract was found to cause a significant inhibition of rat liver cytosolic alcohol dehydrogenase activity. Systematic fractionation of active tractions monitored by bioassay led to isolation of four compounds; aloe-emodin, aloenin, ethylidene-aloenin and
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