Synthesis and Biological Activity of Indazole-Derived HMG-CoA Reductase Inhibitors

  • 발행 : 1995.06.01

초록

New hypolipaemic agents, in which substituted indazole nucleus is connected to tetrahydro-4-hydroxy-2H-pyran-2-one by a two-carbon bridge, were designed and synthesized to show significant inhibitory activity against microsomal HMG-CoA reductase in rat liver.

키워드