대한수의학회지 (Korean Journal of Veterinary Research)
- 제34권2호
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- Pages.259-266
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- 1994
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
토끼에서 oxytetracycline의 정맥 및 근육 투여시의 약물동태학
Pharmacokinetics of oxytetracycline in rabbits after intravenous and intramuscular administrations
- Kim, Eun-jung (Colleage of Veterinary Medicine, Chungnam National University) ;
- Yun, Hyo-in (Colleage of Veterinary Medicine, Chungnam National University) ;
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Park, Seung-chun
(Colleage of Veterinary Medicine, Chungnam National University) ;
- Oh, Tae-kwang (Genetic Engineering Research Institute, KAIST) ;
- Cho, Chun-hyung (Veterinary Research Institute)
- 투고 : 1994.04.28
- 발행 : 1994.04.30
초록
The study was carried out to determine the pharmacokinetic parameters after intravenous(iv) and intramuscular(im) administration (10mg/kr) in healthy rabbits. The results obtained through the experiments were summarized as follows: 1. Bioassay (Bacillus cereus 11778) was evaluated very useful for the determination of oxytetracycline(OTC) in the rabbit serum and tissues, with the detection limit of