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ISOLATION AND IDENTIFICATION OF ANAEROBIC RUMEN BACTERIUM, ACTINOMYCES SP. 40 AND ENZYMATIC PROPERTIES OF β-1, 4-ENDOGLUCANASE

  • Min, H.K. (Department of Animal Science and Technology, College of Agriculture and Life Sciences, Seoul National University) ;
  • Choi, Y.J. (Department of Animal Science and Technology, College of Agriculture and Life Sciences, Seoul National University) ;
  • Ha, J.K. (Department of Animal Science and Technology, College of Agriculture and Life Sciences, Seoul National University) ;
  • Cho, K.K. (Department of Animal Science and Technology, College of Agriculture and Life Sciences, Seoul National University) ;
  • Kwon, Y.M. (Department of Animal Science and Technology, College of Agriculture and Life Sciences, Seoul National University) ;
  • Chang, Y.H. (Genetic Engineering Research Institute) ;
  • Lee, S.S. (Department of Animal Science and Technology, College of Agriculture and Life Sciences, Seoul National University)
  • Received : 1993.12.07
  • Accepted : 1994.04.08
  • Published : 1994.09.01

Abstract

A bacterial strain No. 40, which produced extracellular endoglucanase, was isolated from the rumen of Korean native goals and identified to be a genus of Actinomyces sp. The optimum conditions for endoglucanase production in PY-CMC medium were initial pH of 7.0 and 4 days of cultivation at $39^{\circ}C$. When localization of endoglucanase activity of Actinomyces sp. was determined, 68% of the enzyme activity was found in the extracellular fraction, 11% of the activity was detected in the periplasmic space and the remaining activity was in the intracellular and cell-bound fractions. The maximal endoglucanase activity was observed at pH 5.0 and it was most s table at pH 5.0. The optimum temperature of this enzyme activity was $55^{\circ}C$, but enzyme activity was gradually lost at temperature above $60^{\circ}C$. The crude enzyme was activated by addition of 10 mM cysteine and 10 mM DTT. But it was inhibited by addition of 10 mM $Cu^{{+}{+}}$ and $Fe^{{+}{+}}$. This crude enzyme could digest carboxymethylcellulose (CMC), and degrade xylan, avicel, pNPG, and pNPC to a less extent.

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