Journal of Periodontal and Implant Science
- Volume 24 Issue 1
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- Pages.98-108
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- 1994
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
EFFECTS OF LIPOPOLYSACCHARIDES, URSOLIC ACID AND OLEANOLIC ANCID ON PHENYTOIN-INDUCED CELL ACTIVITY IN HUMAN GINGIVAL FIBROBLAST
인체 치은섬유모세포에서 Lipopolysaccharides, Ursolic acid와 Oleanolic acid에 의한 Phenytoin 유도 세포활성에 미치는 영향
- Kwon, Oh-Dal (Department of Periodontology, College of Dentistry, Wonkwang University) ;
- Kim, Yoon-Sung (Department of Periodontology, College of Dentistry, Wonkwang University) ;
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Shin, Hyung-Shik
(Department of Periodontology, College of Dentistry, Wonkwang University)
- Published : 1994.04.30
Abstract
Gingival hyperplasia is frequently associated with the long-term use of phenytoin for control of convulsive disorder. The purpose of this study was to investigate on the effects of lipopolysaccharides (LPS), ursolic acid and oleanolic acid to phenytoin-induced cell activity in human gingival fibroblast. Human gingival fibroblasts were cultured form the healthy gingiva of orthodontic patients. Gingival fibroblasts were trypsinized and transferred to the weels of microtest plates. Fibroblast were cultured in growth medium added
Keywords
- phenytoin;
- cell activity;
- cultured human gingival fibroblast;
- gingival hyperplasia;
- oleanolic acid;
- ursolic acid