정상인의 혈중 알코올 탈수소효소 활성도 및 에탄올, 아세트알데히드 농도에 관한 연구

Activity of Alcohol Dehydrogenase and Ethanol, Acetaldehyde Levels in Normal Adults Blood

  • 김기웅 (한국산업안전공단 산업보건연구원) ;
  • 양정선 (한국산업안전공단 산업보건연구원) ;
  • 이종성 (한국산업안전공단 산업보건연구원) ;
  • 조영숙 (한국산업안전공단 산업보건연구원) ;
  • 강성규 (한국산업안전공단 산업보건연구원) ;
  • 정호근 (한국산업안전공단 산업보건연구원)
  • Kim, Ki-Woong (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
  • Yang, Jeong Sun (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
  • Lee, Jong-Seong (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
  • Cho, Young-Sook (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
  • Kang, Seong-Kyu (Industrial Health Research Institute, Korea Industrial Safety Corporation) ;
  • Chung, Ho Keun (Industrial Health Research Institute, Korea Industrial Safety Corporation)
  • 발행 : 1994.11.30

초록

To identify normal levels of ethanol, acetaldehyde and alcohol dehydrogenase(ADH) activity in blood of Koreans, ethanol and acetaldehyde levels, activity of ADH in blood of Koreans, ethanol and acetaldehyde levels, activity of ADH in blood were measured in 97 subjects(male : 36, female : 61), 45 subjects(male : 21, female : 24) were not exposed to organic solvents and any other chemicals. Fifty two subjects(male : 15, female : 37) were exposed to organic solvents including toluene and xylene. The results were summerized as follows : 1. The blood ADH was not detected in exposed and non-exposed group. 2. The average blood ethanol level of non-exposed group was 0.0490 mg/dl, and exposed group was 0.0363 mg/dl. They were statistically significant(p<0.05). 3. The blood acetaldehyde levels in exposed group were significantly higher than that of non-exposed group was not statistically significant (p>0.05). 4. The average blood ethanol level of males in both groups was significantly higher than that of females, however, they were not statistically significant (p>0.05).

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