The Korean Journal of Nuclear Medicine (대한핵의학회지)
- Volume 28 Issue 3
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- Pages.282-292
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- 1994
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- 1225-6714(pISSN)
Influence of Ischemic Lesions on $^{99m}Tc$ -HMPAO SPECT Findings in the Diagnosis of Alzheimer's Disease
$^{99m}Tc$ -HMPAO SPECT를 이용한 알쯔하이머병의 진단에서 허혈성 뇌병변이 미치는 영향
- Lee, Kyung-Han (Departments of Nuclear Medicine, Seoul National University College of Medicine) ;
- Lee, Myung-Chul (Departments of Nuclear Medicine, Seoul National University College of Medicine) ;
- Lee, Dong-Soo (Departments of Nuclear Medicine, Seoul National University College of Medicine) ;
- Kwon, June-Soo (Department of Psychiatry, Seoul National University College of Medicine) ;
- Kim, Jong-Ho (Departments of Nuclear Medicine, Seoul National University College of Medicine) ;
- Chung, June-Key (Departments of Nuclear Medicine, Seoul National University College of Medicine) ;
- Woo, Jong-In (Department of Psychiatry, Seoul National University College of Medicine) ;
- Koh, Chang-Soon (Departments of Nuclear Medicine, Seoul National University College of Medicine)
- 이경한 (서울대학교병원 핵의학과) ;
- 이명철 (서울대학교병원 핵의학과) ;
- 이동수 (서울대학교병원 핵의학과) ;
- 권준수 (서울대학교병원 신경정신과) ;
- 김종호 (서울대학교병원 핵의학과) ;
- 정준기 (서울대학교병원 핵의학과) ;
- 우종인 (서울대학교병원 신경정신과) ;
- 고창순 (서울대학교병원 핵의학과)
- Published : 1994.11.30
Abstract
Brain perfusion SPECT shows typical regional perfusion abnormalities in Alzheimer's disease(AD) and is useful for its diagnosis. However, there is also arguement that these patterns show significant overlap with other causes, and the accuracy for SPECT in differentiating AD has shown conflicting results. We postulate that the variation in re-ported results are partly due to a difference in patient or control selection with special reference to the mixture of ischemic cerebral disease in the studied population. To deter-mine the effect of ischemic lesions and the nature of control subjects on SPECT studies for AD, we performed
본 연구에서는
Keywords
- Alzheimer's disease;
- Dementia;
- Single photon emission computed tomography;
- Magnetic resonance imaging;
- Ischemic cerebral disease