Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Diaminoplatinum(II) Complexes of Glutamic Acid: Obvious Chelating Isomerization

  • Young-A Lee (Inorganic Chemistry Laboratory, Korea Institute of Science and Technology) ;
  • Jongki Hong (Molecular Structure Laboratory, Korea Basic Science Center) ;
  • Ok-Sang Jung (Inorganic Chemistry Laboratory, Korea Institute of Science and Technology) ;
  • Youn Soo Sohn (Inorganic Chemistry Laboratory, Korea Institute of Science and Technology)
  • Published : 1994.08.20
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Abstract

Coordination isomers of cis-(N-N)Pt(Glu) prepared by reaction of cis-(N-N)Pt($SO_4$) (N-N=2$NH_3$, ethylenediamine(en),(R,R)-1,2-diaminocyclohexane (DACH), N,N,N',N'-tetramethylethylenediamine (TMEDA)) with barium glutamate in water have been monitored and characterized by $^1H-NMR$, $^{13}C-NMR$, IR, and mass spectra. The reaction at room temperature affords the mixture of O,O'-and N, ${\alpha}$ O-chelated platinum(II) complexes. The O,O'-chelate initially formed isomerized to N,${\alpha}$O-chelate on standing for a long time or increasing temperature. The ratio of the two isomers at room temperature depends on the nature of the nitrogen donor coligand (N-N).

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