Plasma Lipids and Fecal Excretion of Lipids in Rats Fed a High Fat Diet, a High Cholesterol Diet or a Low Fat/High Sucrose Diet

고지방식이, 고콜레스테롤식이, 저지방.설탕식이가 희쥐의 혈청지방 및 변지방에 미치는 영향

The effect of feeding various diets on plasma lipids, liver lipids, fecal excretion of lipids and triglyceride secretion rate was studied in Sprague-Dawley rats fed for 1 month diets containing high fat(40% of energy ; HF) high cholesterol(1% ; HC), low fat/high sucrose(70% ; HS) or control diet(CT). Weight gain in HS group but there were no differences in TG contents of HF or HC groups compared to CT group. Fecal excretion of lipid was higher in HC than in HF, HS and CT groups. Hepatic TG secretion was not significantly different in four dietary groups. Accordingly, hypertriglyceridemia shown in HS group does not seem to be resulted from the increased TG secretion rate.