한국식품영양과학회지 (Journal of the Korean Society of Food Science and Nutrition)

  • 제23권2호
  • /
  • Pages.212-218
  • /
  • 1994
  • /
  • 1226-3311(pISSN)
  • /
  • 2288-5978(eISSN)
한국식품영양과학회 (The Korean Society of Food Science and Nutrition)
권호 표지

흰쥐에있어서 메밀채소의 투여가 지질대사에 미치는 효과

Effects of Dietary Buckwheat Vegetables on Lipid Metabolism in Rats

  • 최용순 (강원대학교 생물응용공학과) ;
  • 서정호 (강원대학교 수의학과) ;
  • 김천호 (강원대학교 수의학과) ;
  • 김영미 (강원대학교 식품공학과) ;
  • 함승시 (강원대학교 식품공학과) ;
  • 이상영 (강원대학교 식품공학과)
  • Choi, Yong-Soon (Dept. of Applied Biology and Technology, Kangwon National University) ;
  • Sur, Jung-Ho (Dept. of Veterinary Medicine, Kangwon National University) ;
  • Kim, Cheon-Ho (Dept. of Veterinary Medicine, Kangwon National University) ;
  • Kim, Young-Mi (Dept. of Food Science and Technology, Kangwon National University) ;
  • Ham, Seung-Shi (Dept. of Food Science and Technology, Kangwon National University) ;
  • Lee, Sang-Young (Dept. of Food Science and Technology, Kangwon National University)
  • 발행 : 1994.04.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The effects of dietary buckwheat vegetables on the in vitro HMG-CoA reductase activity and lipids profiles of serum and liver in rats were evaluated . Buckwheat vegetables were cultivated in the range of 1-15cm of the plant height and dried. The content of rutin in the dried vegetables did not varied largely with the differences in the height of the vegetables. The water extract from buckwheat vegetables activited in vitro HMG-CoA reductase, activity up to 150% of control. Male rats were fed on purified diets. supplemented with0.12% cholesterol, containing dried buckwheat vegetables(BWV, 5% of diet) or rutin 90.25% of diet) . Dietary BWV and rutin, compared with basal diet tended to decrease the concentration of serum cholesterol. The ratio of HDL-cholesterol to total cholesterol were higher slightly in the rutin -fed group than in the other groups. The concentration of serum triacylglycerol was lower markedly in the rutin -fed groups than in the control groups, and BWV group being intermediate . The concentration of liver cholesterol was lower significantly in the BWV group than in the other groups. The results show an effective cholesterol-lowering action of buckwheat vegetables in serum and liver of rats fed on cholesterolemic diets. and that the hypocholesterolemic effects of buchwheat vegetables re not likely to be due to the modulation of the cholesterol synthesis rate.

키워드

참고문헌

  1. Nutr. Rev. v.47 Diet and atherogenesis Stehbens,W.E.
  2. 한국영양식량학회지 v.21 혈청콜레스트롤과 3-hydroxy-3-methlglutaryl coenzyme A reductase 최용순;이상영
  3. 한국영양식량학회지 v.20 메밀보충급여가 백서의 혈당 및 혈압에 미치는 영향 최면;김종대;박경숙;오상룡;이상영
  4. 한국영양식량학회지 v.21 인스탄트 메밀국수가 백서의 소화흡수율, 간장 및 혈청지질 농도에 미치는 영향 최용순;안철;심호흠;최면;오상룡;이상영
  5. 현대생약학 생약학연구회(편)
  6. Byull. Eksp. Biol. Med. v.95 Effect of rutin on cholesterol content in dog lymph, blood and tissues Shaikemelva,U.S.
  7. Korean J. Crop Sci. v.37 Vegetable value and producitivity of buckwheat seedlings Choi,B.H.;Park.K.Y.;Park,R.K.
  8. Nippon Shokuhin Kogyo Gakkaishi v.36 Determination of rutin in buckwheat foods by high performance liquid chromatography Ohara,T.;Ohinata,H.;Muramatsu,T.
  9. 한국영양식량학회지 v.20 메밀의 영양성분과 냉동건조막국수의 이화학적 성질 이상영;심호흠;함승시;이해익;최용순;오상룡
  10. Proc. Nutr. Soc. v.32 The chemistry and estimation of fiber Van Soest, P. J.;McQueen,R.W.
  11. Method in Enzymol. v.71 3-hydroxy-3-methylglutaryl CoA reductase from rat liver Kleinsek,D.A.;Dugan,R.E.;Baker,T.A.;Porter,J.W.
  12. J. Nutr. v.107 Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies American Institute of Nutrition
  13. J. Biol. Chem. v.226 A simple method for the isolation and purification of total lipids from animal tissues Folch,J.;Less,M.;Sloane-Stanly,G.H.
  14. Clin. Chim. Acta. v.22 A colorimetric method for estimating serum triglydecerides Fletcher,M.J.
  15. Lipids v.1 Quantitative analysis of phospholipids by thin-layer chromatography Rouser,G.;Siakatos,A.N.;Fleischer,S.
  16. Am. J. Clin. Path. v.26 A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminase Reitman,S.;Frankels,S.
  17. Clin. Chem. v.27 Colorimetric method for free fatty aicds in serum validated by comparison with gas chromatography Brunk,S.D.;Swanson,J.R.
  18. J. Lipid Res. v.33 The discovery and development of HMG-CoA reductase inhibitors Endo,A.
  19. Jpn. J. Exp. Med. v.53 Metabolic fate of $^{14}C$-quercetin in the ACl rat Ueno,I.;Nakano,N.;Hirono,I.
  20. J. Med. Res. v.77 Hypocholesterolemic and hypolipidemic activity of quercetin, a vitamin P-like compound in rats Basarker,P.W.;Nath,N.
  21. Agric. Biol. Chem. v.42 Effects of dietary quercetin on serum lipids Kato,N.;Tosa,N.;Doudou,T.;Imamura,T.
  22. 한국생물공학회지 v.6 식물추출물로부터 3-hydroxy-3-methylglutary coenzyme A reductase의 활성저해제의 탐색 이윤형;신용목;이재은;최용순;이상영
  23. Proc. Natl. Acad. Sci. USA v.82 Dietary saturated triacylglycerols suppress hepatic low density lipoprotein receptor activity in the hamster Spady,D.K.;Dietschy,J.M.
  24. Proc. Soc, Exp. Biol. Med. v.178 Short-term effect of dietary cholesterol on tissue n-6 fatty acids in fat-deficient rats Haung,Y.S.;Horrobin,D.F.;Manku,M.S.