Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
권호 표지

Identification of Insecticidal Compounds from Actinomycetes Isolate No. 1166

방선균 분리주 No. 1166이 생산하는 살충성 물질 구조 동정

  • 오세량 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 이형규 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 최수근 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 김정일 (KIST 유전공학연구소 응용미생물 연구그룹)
  • Published : 1994.08.01
Download PDF
⟨ Previous Next ⟩

Abstract

In the course of screening for insecticidal metabolites from soil microorganisms, Actinomycetes isolate no.1166 was found to produce active metabolites against Musca domestca and Bombyx mori. Three active components from the metabolites were isolated by solvent extraction and chro- matographic techniques and examined their insecticidal activities on Bombyx mori (3rd larvae) by diet feeding bioassay methods. By UV and NMR data analyses, compound I and III were identified as bafilomycin A$_{2}$ and B$_{1}$, respectively and compound II was also estimated to belong to the bafilomycin family from its physico-chemical data and biological properties.

Keywords

References

  1. Agr. Biol. Chem. v.27 Isolation and physiological activities of piericidin A, a natural insecticide produced by Streptomyces Tamura,S.;N.Takahashi;S.Miyamoto;R.Mori;S.Suzuki;J.Nagatsu
  2. Agr. Biol. Chem. v.33 Pesticidal activity of aureothin Oishi,H.;T.Hosokawa;T.Okutomi;K.Suzuki;K.Ando
  3. Tetrahedron Lett. v.25 Bassianolide, a new insecticidal cyclodepsipeptide from beauveria bassiana and verticillium lecanii Suzuki,A.;M.Kanaoka;A.Isogai;S.Murakoshi;M.Ichinoe;S.Tamura
  4. J. Invert. Pathol. v.40 Insecticidal secondary metabolic products from the entomogenous fungus Verticillium lecanii Claydon,N.;J.F.Grove
  5. J. Antibiot. v.37 Discovery, production and purification of the $Na^ +$,$K^ +$ activated ATPase inhibitor, L-681, 110 from the fermentation broth of Streptomyces sp. MA-5038 Huang,L.;G.Albers-Schonberg;R.L.Monaghan;K.Jakubas;S.S.Pong;O.D.Hensens;R.W.Burg;D.A.Ostlind;J.Conroy;E.O.Stapley
  6. Agr. Biol. Chem. v.48 Search for microbial insect growth regulators; L-alanosine as an ecdysis inhibitor Matsumoto,S.;S.Sakuda;A.Isogai;A.Suzuki
  7. J. Antibiot. v.40 Search for microbial insect growth regulators Ⅱ. allosamidin, a novel insect chitinas inhibitor Sakuda,S.;A.Isogal;S.Matsumoto;A.Suzuki
  8. Agr. Biol. Chem. v.52 Okaramine A, a novel indole alkaloid with insecticidal activity, from Penicillium simplicissimum AK-40 Murao,S.;H.Hayashi;K.Takiuchi;M.Arai
  9. Agr. Biol. Chem. v.53 Structure of the novel insecticidal sesquilignan, haedoxan A Taniguchi,E.;K.Imamura;F.Inshibashi;T.Matsui;A.Nishio
  10. Agr. Biol. Chem. v.53 Isolation and identification of three insecticidal principles from the red alga laurencia nipponica Yamada Watanabe,K.;K.Umeda;M.Miyakado
  11. Agr. Biol. Chem. v.53 Isolation and structure of neoannonin, a novel insecticidal compound from the seeds of annona squamosa Kawazu,K.;J.P.Alcantara;A.Kobayashi
  12. Agr. Biol. Chem. v.53 S,N-Heterocycles 3, a novel insecticidal lead compound, 7-trifluoromethy[1,2,4,] triazolo[3,2,-b]-thiazolo[4,5,-b] pyridine Sanemitsu,Y.;Y.Nakayama;T.Yano;Y.Tanabe
  13. Agr. Biol. Chem. v.55 Calyculin E and F, novel insecticidal metabolites from the marine sponge, discodermia sp. Okada,A.;K.Watanabe;K.Umeda;M.Miyakado
  14. J. Antibiot. v.44 New insecticidal metabolites from soil isolate W719 Reddy,K.;G.Jewett;R.Fatig;M.Brockman;C.Hatton;P.Savickas;D.Hasha;C.Snipes
  15. Discovery and Isolation of Microbial Products Screening, classification and identification of microbial products Berdy,J.;M.S.Verral(ed.)
  16. J. Antibiot. v.24 Tetranactin, a new miticidal antibiotic V. quantitative determination of macrotetrolide antibiotics Suzuki,K.;Y.Nawata;K.Ando
  17. Antimicrob. Agents Chemocher. v.15 Avermectins, new family of potent anthelmintic agents; producing organism and fermentation Burg,R.W.;B.M.Miller;E.F.Baker;J.Birnbaum;S.A.Currie;R.Hartman;Y.L.King;R.L.Monaghan;G.Olson;I.Putter;J.B.Tunac;H.Wallick;E.O.Stapley;R.Oiwa;S.Omura
  18. J. Antibiot. v.33 Milbemycins, a new family of macrolide antibiotics; fermentation, isolation and physico-chemical properties Takiguchi,Y.;H.Mishima;M.Okuda;M.Terao
  19. Biology of Actinomycetes '88 New methods for the selective isolation of soil actionomycetes Nonomura,H.;M.Hayakawa;Okami,Y.(ed.);T.Beppu(ed.);H.Ogawara(ed.)
  20. J. Antibiot. v.41 A simple screening method for insecticidal substances from actinomycetes Fabre,B.;E.Armau;G.Etienne;F.Legendre;G.Tiraby
  21. 한국농화학회지 v.37 Streptomyces sp. no. 46이 생산하는 살충성 물질 구조 동정 오세량;이형규;구본탁;최수근;박상구;신병식;박승환;김정일
  22. J. Antibiot. v.37 Metabolic products of microorganisms 224. bafilomycins, a new group of macrolide antibiotics Werner,G.;H.Hagenmaier;H.Drautz;A.Baumgartner;H.Zahner
  23. Tetrahedron Lett. v.28 A conformational study of bafilomycin A, by X-ray crystallography and NMR techniques Baker,G.H.;P.J.Brown;R.J.J.Dorgan;J.R.Everett;S.V.Ley;A.M.Z.Slawin;D.J.William
  24. J. Antibiot. v.41 Setamycin, a 16-membered macrolide antibiotic, identification and nematocidal activity Otoguro,K.;A.Nakagawa;S.Omura
  25. J. Am. Chem. Soc. v.105 Structure of the sodium and potassium ion activated adenosinetriphosphatase inhibitor L-681,110 Hensens,O.D.;R.L.Monaghan;L.Huang;G.Albers-Schonberg
  26. Agr. Biol. Chem. v.49 The structures of novel insecticidal macrolides: bafilomycins D and E, and oxohygrolidin Kretschmer,A.;M.Dorgerloh;M.Deeg;H.Hagenmaier
  27. Agr. Biol. Chem. v.48 The structure of leucanicidin, a novel insecticidal macrolide produced by Streptomyces halstedii Isogai,A.;S.Sakuda;S.Matsumoto;M.Ogura;K.Furihata;H.Seto;A.Suzuki
  28. J. Antibiot. v.37 L-155, 175; a new antiparasitic macrolide fermentation, isolation and structure Goetz,M.A.;P.A.McCormick;R.L.Monaghan;D.A.Ostlind;O.D.Hensens;J.M.Liesch;G.Albers-Schongerg
  29. Tetrahedron Lett. v.23 The structure of a new antibiotic, hygrolidin Seto,H.;H.Akao;K.Furihata;N.Otake
  30. J. Nat. Prod. v.55 Isolation and structure determination of new macrolide antibiotics Hatfield,G.M.;R.W.Woodard