방선균 분리주 No. 1166이 생산하는 살충성 물질 구조 동정

Identification of Insecticidal Compounds from Actinomycetes Isolate No. 1166

  • 오세량 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 이형규 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 최수근 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 김정일 (KIST 유전공학연구소 응용미생물 연구그룹)
  • 발행 : 1994.08.01

초록

In the course of screening for insecticidal metabolites from soil microorganisms, Actinomycetes isolate no.1166 was found to produce active metabolites against Musca domestca and Bombyx mori. Three active components from the metabolites were isolated by solvent extraction and chro- matographic techniques and examined their insecticidal activities on Bombyx mori (3rd larvae) by diet feeding bioassay methods. By UV and NMR data analyses, compound I and III were identified as bafilomycin A$_{2}$ and B$_{1}$, respectively and compound II was also estimated to belong to the bafilomycin family from its physico-chemical data and biological properties.

키워드

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