Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Antitumor and Immunomodulating Activities of the Polysaccharide Fractions from Artemisia selengensis and Artemisia iwayomogi

  • Koo, Kyoung-Ah (Department of Microbiology, College of Natural Sciences, Inje University) ;
  • Kwak, Jong-Hwan (Department of Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Lee, Kang-Ro (Department of Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Zee, Ok-Pyo (Department of Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Woo, Eun-Rhan (Division of Chemstry, Korea Institute of Science and Technology) ;
  • Park, Ho-Kun (Division of Chemstry, Korea Institute of Science and Technology) ;
  • Youn, Hyun-Joo (Department of Microbiology, College of Natural Sciences, Inje University)
  • Published : 1994.10.01
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Abstract

Effects of the polysaccharide fractions purified from Artemisia selengensis and Artemisia iwayomogi on the immune system was studied. The polysaccharide fractions, respectively called ASP1 and AIP1, may interact with macrophages and lymphocytes in spleen, increasing the population of those cell types in vivo and in vitro. Both ASP1 and AIP1 fractions also syuppress transplanted tumor cell growth and augment antibody production. This study suggests that ASP1 and AIP1 fractios may have immunomodulating and antitumor activities.

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