Radiation Oncology Journal
- 제12권1호
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- Pages.81-90
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- 1994
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- 2234-1900(pISSN)
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- 2234-3156(eISSN)
국소 진행된 간암의 방사선 온열치료성적
The Clinical Results of Thermo-Irradiation on the Locally Advanced Hepatoma with or without Hepatic Arterial Chemo-Embolization
- 장홍석 (가톨릭 대학교 의과대학 강남성모병원 치료방사선과) ;
- 윤세철 (가톨릭 대학교 의과대학 강남성모병원 치료방사선과) ;
- 강기문 (가톨릭 대학교 의과대학 강남성모병원 치료방사선과) ;
- 유미령 (가톨릭 대학교 의과대학 강남성모병원 치료방사선과) ;
- 김성환 (가톨릭 대학교 의과대학 강남성모병원 치료방사선과) ;
- 백남종 (가톨릭 대학교 의과대학 강남성모병원 내과) ;
- 윤승규 (가톨릭 대학교 의과대학 강남성모병원 내과) ;
- 김부성 (가톨릭 대학교 의과대학 강남성모병원 내과) ;
- 신경섭 (가톨릭 대학교 의과대학 강남성모병원 치료방사선과)
- Jang Hong Seok (Department of Therapeutic Radiology, Catholic University Medical College) ;
- Yoon Sei Chul (Department of Therapeutic Radiology, Catholic University Medical College) ;
- Kang Ki Mun (Department of Therapeutic Radiology, Catholic University Medical College) ;
- Ryu Mi Ryeong (Department of Therapeutic Radiology, Catholic University Medical College) ;
- Kim Sung Hwan (Department of Therapeutic Radiology, Catholic University Medical College) ;
- Baek Nam Jong (Department of Internal Medicine, Catholic University Medical College) ;
- Yoon Seung Kyoo (Department of Internal Medicine, Catholic University Medical College) ;
- Kim Boo Sung (Department of Internal Medicine, Catholic University Medical College) ;
- Shinn Kyung Sub (Department of Therapeutic Radiology, Catholic University Medical College)
- 발행 : 1994.02.01
초록
Purpose : The aim of this study is to analyze the clinical results of thermo-irradiation treatment for surgically unresectable advanced hepatoma with or without hepatic arterial chemo-embolization (HACE), chemotherapy (CT) and interferon (IFN) therapy. Materials and Methods : Between February 1990 and December 1992, 45 Patients with surgically unresectable advanced hepatomas were treated by thermo-irradiation with or without hepatic arterial chemo-embolization and other treatment modalities. Among them, We analyzed retrospectively 25 patients who received more than three times of hyperthermias. Mean age was 50 years (range : 18-71 years) and male to female ratio was 20 : 5. In the study, treatment was administered as follows : 3 patients received radiation therapy(RT) and hyperthermia (HT). 3 received RT+HT+CT. 3 received RT+HT+HACE. 1 received RT+HT+CT+HACE. 2 received RT+HT+CT+IFN. 10 received RT+HT+HACE+IFN. 3 received RT+HT+CT+HACE+IFN. Radiation therapy was done by a 6 MV linear accelerator Patients were treated with daily fractions of 180 cGy to doses of 11Gy-50Gy (median 30Gy). Local hyperthermia was done by HEH-500C(Omron Co. Japan), 30-45 min/session, 2 sessions/wk and the number of HT sessions ranged from 3 to 17 (median 7 times). 15 patients of 25 were followed by abdominal CT scan or abdominal ultra-sonogram. The following factors were analyzed :Age, histologic grade, sex. number of hyperthermia, total RT dose, hepatic arterial chemo-embolization. Results : Of 25 patients. there were observed tumor regression (partial response and minimal response) in 6 (24
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